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Multiple-bandwidth photoacoustic tomography

Ku, Geng and Wang, Xueding and Stoica, George and Wang, Lihong V. (2004) Multiple-bandwidth photoacoustic tomography. Physics in Medicine and Biology, 49 (7). pp. 1329-1338. ISSN 0031-9155. doi:10.1088/0031-9155/49/7/018.

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Photoacoustic tomography, also referred to as optoacoustic tomography, employs short laser pulses to generate ultrasonic waves in biological tissues. The reconstructed images can be characterized by the convolution of the structure of samples, the laser pulse and the impulse response of the ultrasonic transducer used for detection. Although the laser-induced ultrasonic waves cover a wide spectral range, a single transducer can receive only part of the spectrum because of its limited bandwidth. To systematically analyse this problem, we constructed a photoacoustic tomographic system that uses multiple ultrasonic transducers simultaneously, each at a different central frequency. The photoacoustic images associated with the different transducers were compared and analysed. The system was tested by imaging both mouse brains and phantom samples. The vascular vessels in the brain were revealed by all of the transducers, but the image resolutions differed. The higher frequency detectors provided better image resolution while the lower frequency detectors delineated the major structural traits with a higher signal–noise ratio.

Item Type:Article
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URLURL TypeDescription
Stoica, George0000-0001-8071-4828
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2004 IOP Publishing Ltd. Received 30 September 2003; Published 18 March 2004.
Issue or Number:7
Record Number:CaltechAUTHORS:20161207-145717339
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Official Citation:Geng Ku et al 2004 Phys. Med. Biol. 49 1329
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:72639
Deposited By: Tony Diaz
Deposited On:07 Dec 2016 23:15
Last Modified:12 Jul 2022 19:52

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