A Caltech Library Service

HUA1 and HUA2 Are Two Members of the Floral Homeotic AGAMOUS Pathway

Chen, Xuemei and Meyerowitz, Elliot M. (1999) HUA1 and HUA2 Are Two Members of the Floral Homeotic AGAMOUS Pathway. Molecular Cell, 3 (3). pp. 349-360. ISSN 1097-2765. doi:10.1016/S1097-2765(00)80462-1.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


The identities of the four floral organ types in an Arabidopsis flower are specified by the combinatorial activities of the floral homeotic A, B, and C function genes; AGAMOUS is the only known C function gene. We have identified two genes that interact with AG in the specification of floral structure, HUA1 and HUA2, from a screen for enhancers of a weak ag allele, ag-4. HUA1 and HUA2 are involved in all aspects of AG function. HUA2 encodes a novel protein that contains nuclear localization signals and signature motifs that suggest HUA2, like AG, may be a transcription factor. Molecular analyses suggest that HUA2 (and possibly HUA1) acts to facilitate AG action at the same hierarchical level as AG.

Item Type:Article
Related URLs:
URLURL TypeDescription
Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 1999 Cell Press. Received 4 December 1998, Revised 24 December 1998. We are grateful to Dr. Satoshi Tabata at the Kazusa DNA Research Institute in Japan for providing the P1 clones MYJ24 and MKD15. We thank Dr. Toshiro Ito for providing the AG antibodies. We thank members of the Meyerowitz lab, C.-F. Chuang, C. Baker, J. Fletcher, T. Ito, C. Ohno, R. Sablowski, D. Wagner, and E. Ziegelhoffer for their comments on the manuscript. X. C. was supported by the National Institutes of Health postdoctoral fellowship #GM17512–02. This work was supported by NIH grant GM 45697 to E. M. M.
Funding AgencyGrant Number
NIH Postdoctoral FellowshipGM17512-02
Issue or Number:3
Record Number:CaltechAUTHORS:20161212-161518999
Persistent URL:
Official Citation:Xuemei Chen, Elliot M Meyerowitz, HUA1 and HUA2 Are Two Members of the Floral Homeotic AGAMOUS Pathway, Molecular Cell, Volume 3, Issue 3, March 1999, Pages 349-360, ISSN 1097-2765, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:72741
Deposited By: George Porter
Deposited On:13 Dec 2016 02:29
Last Modified:11 Nov 2021 05:06

Repository Staff Only: item control page