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A Homolog of NO APICAL MERISTEM Is an Immediate Target of the Floral Homeotic Genes APETALA3/PISTILLATA

Sablowski, Robert W. M. and Meyerowitz, Elliot M. (1998) A Homolog of NO APICAL MERISTEM Is an Immediate Target of the Floral Homeotic Genes APETALA3/PISTILLATA. Cell, 92 (1). pp. 93-103. ISSN 0092-8674. http://resolver.caltech.edu/CaltechAUTHORS:20161214-153236893

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Abstract

To understand how homeotic genes affect morphogenesis and differentiation, their target genes must be identified. In Arabidopsis flowers, the homeotic protein heterodimer APETALA3/PISTILLATA is necessary for petal and stamen formation. Here, AP3/PI function was put under posttranslational control to analyze its immediate effect on the floral mRNA population, with indirect effects blocked by cycloheximide. Using differential display, a target gene of AP3/PI was identified (NAP: NAC-LIKE, ACTIVATED BY AP3/PI), which is homologous to genes required for meristem establishment and separation of floral organs. The expression pattern of NAP and the phenotypes caused by its misexpression suggest that it functions in the transition between growth by cell division and cell expansion in stamens and petals.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S0092-8674(00)80902-2DOIArticle
http://www.sciencedirect.com/science/article/pii/S0092867400809022PublisherArticle
http://dx.doi.org/10.1016/S0092-8674(00)80950-2ErrataErratum
ORCID:
AuthorORCID
Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 1998 Cell Press. Received 3 November 1997, Revised 24 November 1997. We are grateful to L. Medrano for help with restriction fragment length polymorphism mapping, T. Jack for pF730, B. Krizek for the 35S::PI plasmid, A. Lloyd for pBI-ΔGR, J. L. Riechmann for PromoterFinder libraries, M. Callahan for help with PCR genotyping, P. Koen for help with scanning electron microscopy, and to K. Baker, X. Chen, C. -F. Chuang, J. Fletcher, J. Hua, T. Ito, C. Ohno, J. L. Riechmann, K. Roberg, D. Wagner, R. Williams, and E. Ziegelhoffer for critical reading of the manuscript. R. W. M. S. was supported by a long-term fellowship (LT-12/95) from the Human Frontier Science Program, and work in E. M. M.’s laboratory is supported by National Science Foundation grant MCB-9603821. The GenBank accession number for the new gene sequence reported in this paper is AJ222713.
Funders:
Funding AgencyGrant Number
Human Frontier Science ProgramLT-12/95
NSFMCB-9603821
Record Number:CaltechAUTHORS:20161214-153236893
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20161214-153236893
Official Citation:Robert W.M Sablowski, Elliot M Meyerowitz, A Homolog of NO APICAL MERISTEM Is an Immediate Target of the Floral Homeotic Genes APETALA3/PISTILLATA, Cell, Volume 92, Issue 1, 9 January 1998, Pages 93-103, ISSN 0092-8674, http://dx.doi.org/10.1016/S0092-8674(00)80902-2. (http://www.sciencedirect.com/science/article/pii/S0092867400809022)
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ID Code:72834
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:15 Dec 2016 16:32
Last Modified:15 Dec 2016 16:32

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