CaltechAUTHORS
  A Caltech Library Service

The Function and Organization of the Motor System Controlling Flight Maneuvers in Flies

Lindsay, Theodore and Sustar, Anne and Dickinson, Michael (2017) The Function and Organization of the Motor System Controlling Flight Maneuvers in Flies. Current Biology, 27 (3). pp. 345-358. ISSN 0960-9822. https://resolver.caltech.edu/CaltechAUTHORS:20170126-154336284

[img] PDF (Document S1. Supplemental Experimental Procedures and Figures S1-S4) - Supplemental Material
See Usage Policy.

2925Kb
[img] Video (MPEG) (Movie S1. Evaluation of Unmixing Procedure, Related to Figure 1) - Supplemental Material
See Usage Policy.

13Mb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20170126-154336284

Abstract

Animals face the daunting task of controlling their limbs using a small set of highly constrained actuators. This problem is particularly demanding for insects such as Drosophila, which must adjust wing motion for both quick voluntary maneuvers and slow compensatory reflexes using only a dozen pairs of muscles. To identify strategies by which animals execute precise actions using sparse motor networks, we imaged the activity of a complete ensemble of wing control muscles in intact, flying flies. Our experiments uncovered a remarkably efficient logic in which each of the four skeletal elements at the base of the wing are equipped with both large phasically active muscles capable of executing large changes and smaller tonically active muscles specialized for continuous fine-scaled adjustments. Based on the responses to a broad panel of visual motion stimuli, we have developed a model by which the motor array regulates aerodynamically functional features of wing motion.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/j.cub.2016.12.018DOIArticle
http://www.sciencedirect.com/science/article/pii/S0960982216314658PublisherArticle
ORCID:
AuthorORCID
Dickinson, Michael0000-0002-8587-9936
Additional Information:© 2016 Elsevier Ltd. Received 18 October 2016, Revised 6 December 2016, Accepted 8 December 2016, Available online 26 January 2017, Published: January 26, 2017. We would like to thank Peter Weir for suggesting several insightful analyses. This work was supported by a grant from the National Science Foundation (IOS 1452510). Author Contributions: Conceptualization, M.D. and T.L.; Methodology, T.L., M.D., and A.S.; Investigation, T.L. and A.S.; Writing – Original Draft, T.L. and M.D.; Writing – Review & Editing, T.L., M.D., and A.S.; Funding Acquisition, M.D.; Resources, M.D.; Supervision, M.D. Accession Numbers: The accession number for the data reported in this paper is Dryad: http://dx.doi.org/10.5061/dryad.23nm1.
Group:Tianqiao and Chrissy Chen Institute for Neuroscience
Funders:
Funding AgencyGrant Number
NSFIOS-1452510
Subject Keywords:flight; muscles; motor control; sparse networks; in vivo calcium imaging; Drosophila
Issue or Number:3
Record Number:CaltechAUTHORS:20170126-154336284
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170126-154336284
Official Citation:Theodore Lindsay, Anne Sustar, Michael Dickinson, The Function and Organization of the Motor System Controlling Flight Maneuvers in Flies, Current Biology, Volume 27, Issue 3, 6 February 2017, Pages 345-358, ISSN 0960-9822, http://dx.doi.org/10.1016/j.cub.2016.12.018. (http://www.sciencedirect.com/science/article/pii/S0960982216314658)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:73761
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:26 Jan 2017 23:53
Last Modified:03 Oct 2019 16:31

Repository Staff Only: item control page