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Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration

Xu, Minghua and Wang, Lihong V. (2002) Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration. Medical Physics, 29 (8). pp. 1661-1669. ISSN 0094-2405. http://resolver.caltech.edu/CaltechAUTHORS:20170201-140855040

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Abstract

Our study on pulsed-microwave-induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross-sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two-dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half-maximum (FWHM) of the point-spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (∼mm).


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1118/1.1493778DOIArticle
http://onlinelibrary.wiley.com/doi/10.1118/1.1493778/abstractPublisherArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2002 American Association of Physicists in Medicine. Received 12 December 2001; accepted for publication 7 May 2002; published 16 July 2002. This project was sponsored in part by the U.S. Army Medical Research and Material Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grant No. R01 CA71980, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0123-1999.
Funders:
Funding AgencyGrant Number
Army Medical Research and Materiel CommandDAMD17-00-1-0455
NIHR01 CA71980
NSFBES-9734491
Texas Higher Education Coordinating BoardARP 000512-0123-1999
Subject Keywords:microwave, thermoacoustics, tomography, imaging, filtered backprojection
Record Number:CaltechAUTHORS:20170201-140855040
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20170201-140855040
Official Citation:Xu, M. and Wang, L. V. (2002), Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration. Med. Phys., 29: 1661–1669. doi:10.1118/1.1493778
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:73945
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:02 Feb 2017 03:38
Last Modified:02 Feb 2017 03:38

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