Xu, Minghua and Wang, Lihong V. (2002) Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration. Medical Physics, 29 (8). pp. 1661-1669. ISSN 0094-2405. doi:10.1118/1.1493778. https://resolver.caltech.edu/CaltechAUTHORS:20170201-140855040
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Abstract
Our study on pulsed-microwave-induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross-sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two-dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half-maximum (FWHM) of the point-spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (∼mm).
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| Additional Information: | © 2002 American Association of Physicists in Medicine. Received 12 December 2001; accepted for publication 7 May 2002; published 16 July 2002. This project was sponsored in part by the U.S. Army Medical Research and Material Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grant No. R01 CA71980, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0123-1999. | ||||||||||
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| Subject Keywords: | microwave, thermoacoustics, tomography, imaging, filtered backprojection | ||||||||||
| Issue or Number: | 8 | ||||||||||
| DOI: | 10.1118/1.1493778 | ||||||||||
| Record Number: | CaltechAUTHORS:20170201-140855040 | ||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20170201-140855040 | ||||||||||
| Official Citation: | Xu, M. and Wang, L. V. (2002), Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration. Med. Phys., 29: 1661–1669. doi:10.1118/1.1493778 | ||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||
| ID Code: | 73945 | ||||||||||
| Collection: | CaltechAUTHORS | ||||||||||
| Deposited By: | Tony Diaz | ||||||||||
| Deposited On: | 02 Feb 2017 03:38 | ||||||||||
| Last Modified: | 11 Nov 2021 05:23 |
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