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Special Section Guest Editorial - Tissue Polarimetry

Wang, Lihong V. and Coté, Gerard L. and Jacques, Steven L. (2002) Special Section Guest Editorial - Tissue Polarimetry. Journal of Biomedical Optics, 7 (3). p. 278. ISSN 1083-3668. doi:10.1117/1.1489434. https://resolver.caltech.edu/CaltechAUTHORS:20170201-142444792

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Abstract

Tissue polarimetry is an emerging area of technology development in tissue optics that is expected to lead to important research applications in biology and medicine. Traditional polarimetry is a mature field, but its application to thick tissues has been hindered by technical hurdles associated with multiple light scattering. However, light is intrinsically polarized; and many biological tissue components or molecules—such as collagen, muscle fibers, keratin, retina, and glucose—possess polarization properties. Further, biological scatterers—such as cell nuclei and mitochondria—alter light polarization upon each scattering event according to the geometric and optical parameters of the scatterers. Since incident polarized light is rapidly depolarized by scattering, polarization-sensitive detection of reflected or transmitted light selects only the early escaping photons and rejects multiply scattered light. Hence, polarized light offers a means of gating: reflected polarized photons interrogate superficial tissue layers, whereas transmitted polarized photons image the ballistic or quasi-ballistic region. Polarization can therefore provide novel contrast mechanisms for imaging, diagnosis, and sensing.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1117/1.1489434DOIArticle
http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=1101485PublisherArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2002 Society of Photo-Optical Instrumentation Engineers. Online August 01, 2002.
Issue or Number:3
DOI:10.1117/1.1489434
Record Number:CaltechAUTHORS:20170201-142444792
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170201-142444792
Official Citation:Wang LV, Coté GL, Jacques SL; Special section guest editorial. J. Biomed. Opt. 0001;7(3):278-278
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:73952
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:01 Feb 2017 22:59
Last Modified:11 Nov 2021 05:23

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