CaltechAUTHORS
  A Caltech Library Service

The effect of face patch microstimulation on perception of faces and objects

Moeller, Sebastian and Crapse, Trinity and Chang, Le and Tsao, Doris Y. (2017) The effect of face patch microstimulation on perception of faces and objects. Nature Neuroscience, 20 (5). pp. 743-752. ISSN 1097-6256. http://resolver.caltech.edu/CaltechAUTHORS:20170201-195823032

[img] Image (JPEG) (Supplementary Figure 1: Mean change in performance caused by microstimulation of each face patch) - Supplemental Material
See Usage Policy.

52Kb
[img] Image (JPEG) (Supplementary Figure 2: The dependence of effect magnitude for faces on stimulation current strength) - Supplemental Material
See Usage Policy.

169Kb
[img] Image (JPEG) (Supplementary Figure 3: The dependence of effect magnitude for round objects on stimulation current strength and electrode position, for subject M1 for three different sessions) - Supplemental Material
See Usage Policy.

132Kb
[img] Image (JPEG) (Supplementary Figure 4: The dependence of effect magnitude on proximity of the stimulation site to the center of the face patch, for the five different object categories from Experiment 3) - Supplemental Material
See Usage Policy.

179Kb
[img] Image (JPEG) (Supplementary Figure 5: Experiment 2: effect of stimulation inside face patch AM on the perception of nonround objects) - Supplemental Material
See Usage Policy.

69Kb
[img] Image (JPEG) (Supplementary Figure 6: Experiment 4b: effect of stimulation inside face patch AM on perception of non-face objects II in M2) - Supplemental Material
See Usage Policy.

77Kb
[img] Image (JPEG) (Supplementary Figure 7: Electrode position for M1 showing that, for the data presented in Figure 7, the electrode tip was located inside face patch AM) - Supplemental Material
See Usage Policy.

120Kb
[img] Image (JPEG) (Supplementary Figure 8: Activation to faces, cartoon houses, real houses and real objects) - Supplemental Material
See Usage Policy.

316Kb
[img] Image (JPEG) (Supplementary Figure 9: Experiment 5: dependence of effect magnitude on stimulation timing) - Supplemental Material
See Usage Policy.

167Kb
[img] Image (JPEG) (Supplementary Figure 10: Analysis of data in Supplementary Figure 9, separating data for each of 32 different cue 2 identities) - Supplemental Material
See Usage Policy.

214Kb
[img] Image (JPEG) (Supplementary Figure 11: Behavioral performance from training sessions and from experimental sessions from nonmicrostimulated trials) - Supplemental Material
See Usage Policy.

204Kb
[img] Image (JPEG) (Supplementary Figure 12: Neuronal response selectivity at the different stimulation sites, across animals) - Supplemental Material
See Usage Policy.

324Kb
[img] PDF (Supplementary Figures 1–12 and Supplementary Tables 1–4) - Supplemental Material
See Usage Policy.

4Mb
[img] PDF (2.Supplementary Methods Checklist) - Supplemental Material
See Usage Policy.

472Kb
[img] MS Excel (Selected statistics for Supplementary Figure 10) - Supplemental Material
See Usage Policy.

20Kb

Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:20170201-195823032

Abstract

What is the range of stimuli encoded by face-selective regions of the brain? We asked how electrical microstimulation of face patches in macaque inferotemporal cortex affects perception of faces and objects. We found that microstimulation strongly distorted face percepts and that this effect depended on precise targeting to the center of face patches. While microstimulation had no effect on the percept of many non-face objects, it did affect the percept of some, including non-face objects whose shape is consistent with a face (for example, apples) as well as somewhat facelike abstract images (for example, cartoon houses). Microstimulation even perturbed the percept of certain objects that did not activate the stimulated face patch at all. Overall, these results indicate that representation of facial identity is localized to face patches, but activity in these patches can also affect perception of face-compatible non-face objects, including objects normally represented in other parts of inferotemporal cortex.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://dx.doi.org/10.1038/nn.4527DOIArticle
http://www.nature.com/neuro/journal/v20/n5/full/nn.4527.htmlPublisherArticle
http://rdcu.be/p271PublisherFree ReadCube access
Additional Information:© 2017 Macmillan Publishers Limited. Received 14 September 2016; accepted 30 January 2017; published online 13 March 2017. We thank N. Schweers for technical support, as well as N. Kanwisher, S. Kornblith, M. Livingstone, members of the Tsao lab and the three anonymous reviewers for critical comments. This work was supported by the Howard Hughes Medical Institute, the National Institutes of Health (1R01EY019702) and the Humboldt Foundation (to S.M.). Author Contributions: S.M. and D.Y.T. designed the experiments, interpreted the data and wrote the paper. S.M. and D.Y.T. conducted all experiments except those shown in Figure 6, which were done by T.C. and L.C., and Supplementary Figure 8, which was done by L.C. S.M. analyzed the data. Data availability. The data that support the findings of this study are available from the corresponding author upon reasonable request. Code availability. The code used to analyze the data in this study is available from the corresponding author upon reasonable request. Ethics. All procedures conformed to Caltech IACUC and US National Institutes of Health guidelines, including the US National Institutes of Health Guide for Care and Use of Laboratory Animals. The authors declare no competing financial interests.
Group:Tianqiao and Chrissy Chen Institute for Neuroscience
Funders:
Funding AgencyGrant Number
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
NIH1R01EY019702
Alexander von Humboldt FoundationUNSPECIFIED
Record Number:CaltechAUTHORS:20170201-195823032
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20170201-195823032
Official Citation:The effect of face patch microstimulation on perception of faces and objects Sebastian Moeller, Trinity Crapse, Le Chang & Doris Y Tsao Nature Neuroscience (2017) doi:10.1038/nn.4527
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:73973
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:13 Mar 2017 18:40
Last Modified:22 May 2018 17:22

Repository Staff Only: item control page