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Signal processing in scanning thermoacoustic tomography in biological tissues

Xu, Yuan and Wang, Lihong V. (2001) Signal processing in scanning thermoacoustic tomography in biological tissues. Medical Physics, 28 (7). pp. 1519-1524. ISSN 0094-2405. doi:10.1118/1.1380436.

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Microwave-induced thermoacoustic tomography was explored to image biological tissues. Short microwave pulses irradiated tissues to generate acoustic waves by thermoelastic expansion. The microwave-induced thermoacoustic waves were detected with a focused ultrasonic transducer to obtain two-dimensional tomographic images of biological tissues. The dependence of the axial and the lateral resolutions on the spectra of the signals was studied. A reshaping filter was applied to the temporal piezoelectric signals from the transducer to increase the weight of the high-frequency components, which improved the lateral resolution, and to broaden the spectrum of the signal, which enhanced the axial resolution. A numerical simulation validated our signal-processing approach.

Item Type:Article
Related URLs:
URLURL TypeDescription
Xu, Yuan0000-0001-9326-2197
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2001 American Association of Physicists in Medicine. Received 12 December 2000; accepted for publication 27 March 2001. We thank G. Ku for experimental assistance. This project was sponsored in part by the U.S. Army Medical Research and Materiel Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grants No. R01 CA71980 and No. R21 CA83760, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0123-1999.
Funding AgencyGrant Number
Army Medical Research and Materiel CommandDAMD17-00-1-0455
NIHR01 CA71980
NIHR21 CA83760
Texas Higher Education Coordinating BoardARP 000512-0123-1999
Subject Keywords:microwave; ultrasonics; thermoacoustics; tomography; resolution; filter
Issue or Number:7
Record Number:CaltechAUTHORS:20170203-140443612
Persistent URL:
Official Citation:Xu, Y. and Wang, L. V. (2001), Signal processing in scanning thermoacoustic tomography in biological tissues. Med. Phys., 28: 1519–1524. doi:10.1118/1.1380436
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74039
Deposited By: Tony Diaz
Deposited On:03 Feb 2017 23:38
Last Modified:11 Nov 2021 05:24

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