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Frequency-swept ultrasound-modulated optical tomography in biological tissue by use of parallel detection

Yao, Gang and Jiao, Shuliang and Wang, Lihong V. (2000) Frequency-swept ultrasound-modulated optical tomography in biological tissue by use of parallel detection. Optics Letters, 25 (10). pp. 734-736. ISSN 0146-9592. http://resolver.caltech.edu/CaltechAUTHORS:20170203-143419144

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Abstract

A frequency-swept ultrasonic beam was focused into a biological tissue sample to modulate the laser light passing through the ultrasonic beam inside the tissue. Parallel detection of the speckle field formed by the transmitted laser light was implemented with the source-synchronous-illumination lock-in technique to improve the signal-to-noise ratio. The ultrasound-modulated laser light reflects the local optical and mechanical properties in the ultrasonic beam and can be used for tomographic imaging of the tissue. Sweeping the ultrasonic frequency provides spatial resolution along the ultrasonic axis, which is scalable with the frequency span of the sweep. Two-dimensional images of biological tissue with buried objects were successfully obtained experimentally.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1364/OL.25.000734DOIArticle
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-25-10-734PublisherArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2000 Optical Society of America. Received January 7, 2000. This project was sponsored in part by National Institutes of Health grants R29 CA68562, R01 CA71980, and R21 CA83760 and by National Science Foundation grant BES-9734491.
Funders:
Funding AgencyGrant Number
NIHR29 CA68562
NIHR01 CA71980
NIHR21 CA83760
NSFBES-9734491
Classification Code:OCIS codes: 170.3880, 120.6150, 110.7050, 110.7170
Record Number:CaltechAUTHORS:20170203-143419144
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20170203-143419144
Official Citation:Gang Yao, Shuliang Jiao, and Lihong V. Wang, "Frequency-swept ultrasound-modulated optical tomography in biological tissue by use of parallel detection," Opt. Lett. 25, 734-736 (2000)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74041
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:04 Feb 2017 02:43
Last Modified:04 Feb 2017 02:43

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