Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide A

Fuerst, Douglas E. and Stoltz, Brian M. and Wood, John L. (2000) Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide A. Organic Letters, 2 (22). pp. 3521-3523. ISSN 1523-7060. doi:10.1021/ol006578v. https://resolver.caltech.edu/CaltechAUTHORS:20170215-134104826

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Abstract

Two complementary strategies for the synthesis of the diazonamide A bisaryl quaternary center are described. The first strategy relies upon an extremely facile tandem cyclopropanation/ring-opening sequence, which has proven amenable to chiral catalysis to provide enantioenriched material. The second strategy relies upon a more concise alkylation route ideal for material advancement.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1021/ol006578v	DOI	Article
http://pubs.acs.org/doi/suppl/10.1021/ol006578v	Publisher	Supporting Information

ORCID:

Author	ORCID
Stoltz, Brian M.	0000-0001-9837-1528

Additional Information:

© 2000 American Chemical Society. Received September 11, 2000. Publication Date (Web): October 4, 2000. We are pleased to acknowledge the support of this investigation by Bristol-Myers Squibb, Yamanouchi, Pfizer, and Merck. J.L.W. is a fellow of the Alfred P. Sloan Foundation.

Funders:

Funding Agency	Grant Number
Bristol-Myers Squibb	UNSPECIFIED
Yamanouchi	UNSPECIFIED
Pfizer	UNSPECIFIED
Merck	UNSPECIFIED
Alfred P. Sloan Foundation	UNSPECIFIED

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DOI:

10.1021/ol006578v

Record Number:

CaltechAUTHORS:20170215-134104826

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20170215-134104826

Official Citation:

Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide A Douglas E. Fuerst, Brian M. Stoltz, and John L. Wood Organic Letters 2000 2 (22), 3521-3523 DOI: 10.1021/ol006578v

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ID Code:

74329

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CaltechAUTHORS

Deposited By:

George Porter

Deposited On:

15 Feb 2017 22:40

Last Modified:

11 Nov 2021 05:26

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