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The Biology and Chemistry of the Zoanthamine Alkaloids

Behenna, Douglas C. and Stockdill, Jennifer L. and Stoltz, Brian M. (2008) The Biology and Chemistry of the Zoanthamine Alkaloids. Angewandte Chemie International Edition, 47 (13). pp. 2365-2386. ISSN 1433-7851. doi:10.1002/anie.200703172.

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Marine natural products have long played an important role in natural products chemistry and drug discovery. Mirroring the rich variety and complicated interactions of the marine environment, the substances isolated from sea creatures tend to be incredibly diverse in both molecular structure and biological activity. The natural products isolated from the polyps of marine zoanthids are no exception. The zoanthamine alkaloids, the first of which were isolated over 20 years ago, are of particular interest to the synthetic community because they feature a novel structural framework and exhibit a broad range of biological activities. In this Review, we summarize the major contributions to understanding the zoanthamine natural products with regard to their isolation and structure determination, as well as studies on their biological activity and total synthesis.

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Stoltz, Brian M.0000-0001-9837-1528
Additional Information:© 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: July 16, 2007; Published online: February 28, 2007. We thank for the use of pictures of zoanthids throughout this Review, and Teresa Barth for assistance with the design of the graphics and frontispiece.
Subject Keywords:alkaloids; biological information; cyclic compounds; natural products; organic synthesis
Issue or Number:13
Record Number:CaltechAUTHORS:20170215-151808188
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Official Citation:Behenna, Douglas C., Stockdill, Jennifer L. and Stoltz, Brian M. (2008), The Biology and Chemistry of the Zoanthamine Alkaloids. Angewandte Chemie International Edition, 47: 2365–2386. doi:10.1002/anie.200703172
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74339
Deposited By: Tony Diaz
Deposited On:15 Feb 2017 23:22
Last Modified:11 Nov 2021 05:26

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