Tambar, Uttam K. and Stoltz, Brian M. (2005) The Direct Acyl-Alkylation of Arynes. Journal of the American Chemical Society, 127 (15). pp. 5340-5341. ISSN 0002-7863. doi:10.1021/ja050859m. https://resolver.caltech.edu/CaltechAUTHORS:20170222-085357234
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Abstract
An efficient and mild acyl-alkylation of arynes is described. The method is used to synthesize medium-sized carbocycles by the ring-expansion of cyclic β-ketoesters.
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| Additional Information: | © 2005 American Chemical Society. Received 9 February 2005. Published online 26 March 2005. Published in print 1 April 2005. This work is dedicated to our friend and colleague Professor John D. Roberts, the father of benzyne.8 We are grateful to the NDSEG (predoctoral fellowship to U.K.T.), the A. P. Sloan Foundation, the Research Corporation, Pfizer, Novartis, Merck, Amgen, Lilly, Roche, Abbott, AstraZeneka, GlaxoSmithKline, and Caltech for financial support. | ||||||||||||||||||||||||||||
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| Issue or Number: | 15 | ||||||||||||||||||||||||||||
| DOI: | 10.1021/ja050859m | ||||||||||||||||||||||||||||
| Record Number: | CaltechAUTHORS:20170222-085357234 | ||||||||||||||||||||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20170222-085357234 | ||||||||||||||||||||||||||||
| Official Citation: | The Direct Acyl-Alkylation of Arynes Uttam K. Tambar and Brian M. Stoltz Journal of the American Chemical Society 2005 127 (15), 5340-5341 DOI: 10.1021/ja050859m | ||||||||||||||||||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||||||||||||||||||
| ID Code: | 74457 | ||||||||||||||||||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||||||||||||||||||
| Deposited By: | Ruth Sustaita | ||||||||||||||||||||||||||||
| Deposited On: | 22 Feb 2017 19:38 | ||||||||||||||||||||||||||||
| Last Modified: | 11 Nov 2021 05:27 |
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