Palladium-Catalyzed Enantioselective Oxidation of Alcohols: A Dramatic Rate Acceleration by Cs_2CO_3/t-BuOH

Bagdanoff, Jeffrey T. and Ferreira, Eric M. and Stoltz, Brian M. (2003) Palladium-Catalyzed Enantioselective Oxidation of Alcohols: A Dramatic Rate Acceleration by Cs_2CO_3/t-BuOH. Organic Letters, 5 (6). pp. 835-837. ISSN 1523-7060. doi:10.1021/ol027463p. https://resolver.caltech.edu/CaltechAUTHORS:20170222-145100100

PDF - Supplemental Material
See Usage Policy.
176kB

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20170222-145100100

Abstract

The addition of Cs_2CO_3 and t-BuOH provides a dramatic rate acceleration in the palladium-catalyzed aerobic oxidative kinetic resolution of secondary alcohols while maintaining the selectivity of the process.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1021/ol027463p	DOI	Article
http://pubs.acs.org/doi/suppl/10.1021/ol027463p	Publisher	Supporting Information

ORCID:

Author	ORCID
Stoltz, Brian M.	0000-0001-9837-1528

Additional Information:

© 2003 American Chemical Society. Received 13 December 2002. Published online 14 February 2003. Published in print 1 March 2003. We wish to thank the NIH-NIGMS (R01 GM65961-01), the California Institute of Technology, the Camille and Henry Dreyfus Foundation (New Faculty Award to B.M.S.), the Merck Research Laboratories, Research Corporation, The University of California TRDRP (predoctoral fellowship to J.T.B.), the National Science Foundation (predoctoral fellowship to E.M.F.), GlaxoSmithKline, and Abbott Laboratories for generous financial support.

Funders:

Funding Agency	Grant Number
NIH	R01GM65961-01
Caltech	UNSPECIFIED
Camille and Henry Dreyfus Foundation	UNSPECIFIED
Merck Research Laboratories	UNSPECIFIED
Research Corporation	UNSPECIFIED
California Tobacco-Related Disease Research Program	UNSPECIFIED
NSF Predoctoral Fellowship	UNSPECIFIED
GlaxoSmithKline	UNSPECIFIED
Abbott Laboratories	UNSPECIFIED

Issue or Number:

DOI:

10.1021/ol027463p

Record Number:

CaltechAUTHORS:20170222-145100100

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20170222-145100100

Official Citation:

Palladium-Catalyzed Enantioselective Oxidation of Alcohols: A Dramatic Rate Acceleration by Cs2CO3/t-BuOH Jeffrey T. Bagdanoff, Eric M. Ferreira, and Brian M. Stoltz Organic Letters 2003 5 (6), 835-837 DOI: 10.1021/ol027463p

Usage Policy:

No commercial reproduction, distribution, display or performance rights in this work are provided.

ID Code:

74472

Collection:

CaltechAUTHORS

Deposited By:

Ruth Sustaita

Deposited On:

22 Feb 2017 23:03

Last Modified:

11 Nov 2021 05:27

Repository Staff Only: item control page