A Caltech Library Service

Flow effects on the viability and lysis of suspended mammalian cells

McQueen, Anne and Meilhoc, Eliane and Bailey, James E. (1987) Flow effects on the viability and lysis of suspended mammalian cells. Biotechnology Letters, 9 (12). pp. 831-836. ISSN 0141-5492. doi:10.1007/BF01026191.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


A mouse myeloma cell line growing in suspension was subjected intermittently to flow through a sudden contraction and turbulent flow in a capillary tube. The probability of lysis per pass through the capillary tube increased with average wall shear stress level and with residence time per pass in the tube. Lysis was first observed at a threshold average wall shear stress level of 1800 dyn/cm^2. Although the flow caused lysis, it had no effect on cell viability.

Item Type:Article
Related URLs:
URLURL TypeDescription
Additional Information:© 1987 Science and Technology Letters. First Online: 01 December 1987.
Issue or Number:12
Record Number:CaltechAUTHORS:20170306-101145611
Persistent URL:
Official Citation:McQueen, A., Meilhoc, E. & Bailey, J.E. Biotechnol Lett (1987) 9: 831. doi:10.1007/BF01026191
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74771
Deposited By: Tony Diaz
Deposited On:06 Mar 2017 18:19
Last Modified:11 Nov 2021 05:29

Repository Staff Only: item control page