CaltechAUTHORS
  A Caltech Library Service

Comment on "Evidence of Abundant and Purifying Selection in Humans for Recently Acquired Regulatory Functions"

Bray, Nicolas and Pachter, Lior (2012) Comment on "Evidence of Abundant and Purifying Selection in Humans for Recently Acquired Regulatory Functions". . (Submitted) https://resolver.caltech.edu/CaltechAUTHORS:20170307-101423905

[img] PDF - Submitted Version
See Usage Policy.

52Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20170307-101423905

Abstract

Ward and Kellis (Reports, September 5 2012) identify regulatory regions in the human genome exhibiting lineage-specific constraint and estimate the extent of purifying selection. There is no statistical rationale for the examples they highlight, and their estimates of the fraction of the genome under constraint are biased by arbitrary designations of completely constrained regions.


Item Type:Report or Paper (Discussion Paper)
Related URLs:
URLURL TypeDescription
https://arxiv.org/abs/1212.3076arXivDiscussion Paper
Record Number:CaltechAUTHORS:20170307-101423905
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170307-101423905
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74840
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:07 Mar 2017 18:32
Last Modified:03 Oct 2019 16:43

Repository Staff Only: item control page