Bray, Nicolas and Pachter, Lior (2012) Comment on "Evidence of Abundant and Purifying Selection in Humans for Recently Acquired Regulatory Functions". . (Submitted) https://resolver.caltech.edu/CaltechAUTHORS:20170307-101423905
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Abstract
Ward and Kellis (Reports, September 5 2012) identify regulatory regions in the human genome exhibiting lineage-specific constraint and estimate the extent of purifying selection. There is no statistical rationale for the examples they highlight, and their estimates of the fraction of the genome under constraint are biased by arbitrary designations of completely constrained regions.
| Item Type: | Report or Paper (Discussion Paper) | ||||||
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| Record Number: | CaltechAUTHORS:20170307-101423905 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20170307-101423905 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 74840 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Tony Diaz | ||||||
| Deposited On: | 07 Mar 2017 18:32 | ||||||
| Last Modified: | 24 Feb 2020 10:30 |
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