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Microwave-induced acoustic imaging of biological tissues

Wang, Lihong V. and Zhao, Xuemei and Sun, Haitao and Ku, Geng (1999) Microwave-induced acoustic imaging of biological tissues. Review of Scientific Instruments, 70 (9). pp. 3744-3748. ISSN 0034-6748. doi:10.1063/1.1149986.

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We present tomographic imaging of biological tissues by use of microwave-induced acoustic signal. It was demonstrated that the acoustic signal was proportional to the intensity of the incident microwave and was related to the absorption property of microwave in the medium. Pulsed microwave radiation was used to illuminate the samples. Absorbed microwave energy caused thermoelastic expansion that radiated acoustic waves. A focused ultrasonic transducer detected the time-resolved acoustic signals. Each acoustic signal was converted into a one-dimensional image. A linear scanning of the ultrasonic transducer yielded multiple one-dimensional images, which formed a two-dimensional image. The imaging contrast is based on the difference in the dielectric constants among biological tissues. Because of the large contrast in microwave absorption among different tissue types, microwave-induced acoustic tomography could potentially provide a new modality for detecting early-stage cancers.

Item Type:Article
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Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 1999 American Institute of Physics. Received 19 March 1999; accepted for publication 15 June 1999. This project was sponsored in part by the National Institutes of Health Grant Nos. R29 CA68562 and R01 CA71980 and by the National Science Foundation Grant No. BES-9734491.
Funding AgencyGrant Number
NIHR29 CA68562
NIHR01 CA71980
Issue or Number:9
Record Number:CaltechAUTHORS:20170308-133716543
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:74914
Deposited By: Tony Diaz
Deposited On:08 Mar 2017 21:51
Last Modified:15 Nov 2021 16:29

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