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The effects of pressure on the buoyant behavior of deoxyribonucleic acid and tobacco mosaic virus in a density gradient at equilibrium in the ultracentrifuge

Hearst, John E. and Ifft, James B. and Vinograd, Jerome (1961) The effects of pressure on the buoyant behavior of deoxyribonucleic acid and tobacco mosaic virus in a density gradient at equilibrium in the ultracentrifuge. Proceedings of the National Academy of Sciences of the United States of America, 47 (7). pp. 1015-1025. ISSN 0027-8424. https://resolver.caltech.edu/CaltechAUTHORS:HEApnas61a

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Abstract

In the original analysis(1) of the behavior of macromolecules and viruses in a buoyant density gradient at equilibrium in the ultracentrifuge, all components were assumed to be incompressible. As a few hundred atmospheres are normally generated in the liquid, it is to be expected that previous results based on the assumption of incompressibility require re-examination.


Item Type:Article
Related URLs:
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https://doi.org/10.1073/pnas.47.7.1015DOIUNSPECIFIED
Additional Information:© 1961 by the National Academy of Sciences. Communicated by Linus Pauling, May 29, 1961. This investigation was supported in part by Research Grant H-3394 from the National Institutes of Health, U.S. Public Health Service. [J.E.H. was a] Predoctoral Fellow of the National Science Foundation. [J.B.I. was a] U.S. Public Health Service Research Fellow of the Division of General Medical Sciences. Gates and Crellin Laboratories of Chemistry, Contribtion No. 2701.
Issue or Number:7
Record Number:CaltechAUTHORS:HEApnas61a
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:HEApnas61a
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:7507
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:28 Feb 2007
Last Modified:02 Oct 2019 23:42

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