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Photoacoustic Tomography

Wang, Lihong V. (2010) Photoacoustic Tomography. In: Optical-Thermal Response of Laser-Irradiated Tissue. Springer , Dordrecht, pp. 743-760. ISBN 978-90-481-8830-7.

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Photoacoustic tomography (PAT) refers to imaging that is based on the photoacoustic effect. Although the photoacoustic effect as a physical phenomenon was first reported on by Alexander Graham Bell in 1880 [1], PAT as an imaging technology was developed only after the advent of ultrasonic transducers, computers, and lasers [2–31]. A review on biomedical photoacoustics is available [32]. The motivation for PAT is to combine optical-absorption contrast with ultrasonic spatial resolution for deep imaging in the optical quasi-diffusive or diffusive regime. In PAT, the tissue is irradiated by usually a short-pulsed laser beam to achieve a thermal and acoustic impulse response (Fig. 19.1). Locally absorbed light is converted into heat, which is further converted to a pressure rise via thermo-elastic expansion. The initial pressure rise – determined by the local optical absorption coefficient (μ_â), fluence (ψ) and other thermal and mechanical properties – propagates as an ultrasonic wave, which is referred to as a photoacoustic wave.

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Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2011 Springer Science+Business Media B.V. The author thanks H. Zhang and K. Maslov for providing unpublished Fig. 19.4. This work was sponsored by National Institutes of Health grants R01 EB000712 and R01 NS46214.
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NIHR01 EB000712
NIHR01 NS46214
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:75131
Deposited By: Tony Diaz
Deposited On:15 Mar 2017 18:14
Last Modified:26 Nov 2019 18:55

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