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Evidence for the appearance of novel gene products during amphibian blastulation

Davidson, Eric H. and Crippa, Marco and Mirsky, Alfred E. (1968) Evidence for the appearance of novel gene products during amphibian blastulation. Proceedings of the National Academy of Sciences of the United States of America, 60 (1). pp. 152-159. ISSN 0027-8424. PMCID PMC539095. doi:10.1073/pnas.60.1.152.

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Genetic information begins to be transcribed during early cleavage in amphibian embryos,(1,2) and the tempo of informational RNA synthesis increases gradually through cleavage and into the early blastula stage. Previous studies from this laboratory (3,4) have shown that at this point a remarkable, near embryo-wide acceleration of informational RNA synthesis occurs, resulting during the mid-tolate blastular period in at least a 20-fold increase in the rate of synthesis of heterogeneously sedimenting, DNA-like RNA.

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Additional Information:© 1968 by the National Academy of Sciences. Communicated February 20, 1968. This work was supported by American Cancer Society grant E-334 B and by National Institute of Child Health and Development grant HD 02412-02.
Funding AgencyGrant Number
American Cancer SocietyE-334B
NIHHD 02412-02
Issue or Number:1
PubMed Central ID:PMC539095
Record Number:CaltechAUTHORS:DAVpnas68b
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:7565
Deposited By: Tony Diaz
Deposited On:06 Mar 2007
Last Modified:01 Jun 2023 23:14

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