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Structures of two classes of MHC molecules elucidated: crucial differences and similarities

Bjorkman, Pamela J. and Burmeister, Wilhelm P. (1994) Structures of two classes of MHC molecules elucidated: crucial differences and similarities. Current Opinion in Structural Biology, 4 (6). pp. 852-856. ISSN 0959-440X. https://resolver.caltech.edu/CaltechAUTHORS:20170405-151845800

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Abstract

New structures of MHC molecules have significantly improved our understanding of molecular recognition in cellular immunology. Highlights include the first structure of a class II MHC molecule, complexed with a viral peptide and with a bacterial superantigen. A structure of an MHC-like Fc receptor is expected soon. Interesting comparisons can now be made between the recognition properties of MHC and MHC-like proteins.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/0959-440X(94)90266-6DOIArticle
http://www.sciencedirect.com/science/article/pii/0959440X94902666?via%3DihubPublisherArticle
ORCID:
AuthorORCID
Bjorkman, Pamela J.0000-0002-2277-3990
Additional Information:© 1994 Current Biology Ltd. We thank Kirsten Fischer Lindahl and her colleagues for communicating data before publication and Larry Stern and Ted Jardetzky for the DR1 coordinates. Wim Burmeister is supported by an EMBO fellowship. Work in the authors' laboratory is supported by the Howard Hughes Medical Institute (PJB) and a grant from the Arthritis Foundation (PJB).
Funders:
Funding AgencyGrant Number
European Molecular Biology Organization (EMBO)UNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Arthritis FoundationUNSPECIFIED
Issue or Number:6
Record Number:CaltechAUTHORS:20170405-151845800
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170405-151845800
Official Citation:Pamela J. Bjorkman, Wilhelm P. Burmeister, Structures of two classes of MHC molecules elucidated: crucial differences and similarities, Current Opinion in Structural Biology, Volume 4, Issue 6, 1994, Pages 852-856, ISSN 0959-440X, http://dx.doi.org/10.1016/0959-440X(94)90266-6. (http://www.sciencedirect.com/science/article/pii/0959440X94902666)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:75750
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:05 Apr 2017 23:04
Last Modified:03 Oct 2019 16:53

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