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The (Greek) Key to Structures of Neural Adhesion Molecules

Vaughn, Daniel E. and Bjorkman, Pamela J. (1996) The (Greek) Key to Structures of Neural Adhesion Molecules. Neuron, 16 (2). pp. 261-273. ISSN 0896-6273. doi:10.1016/S0896-6273(00)80045-8. https://resolver.caltech.edu/CaltechAUTHORS:20170406-101209862

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Abstract

Cells need to adhere specifically to cellular and extracellular components of their environment to carry out diverse physiological functions. Examples of such functions within the nervous system include neurite extension, synapse formation, and the myelination of axons. The ability to recognize multiple environmental cues and to undergo specific adhesion is critical to each of these complex cellular functions. Recognition and adhesion are mediated by cell adhesion molecules (CAMs), which bind to macromolecules expressed on neighboring cells or in the extracellular matrix (ECM).


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S0896-6273(00)80045-8DOIArticle
http://www.sciencedirect.com/science/article/pii/S0896627300800458PublisherArticle
ORCID:
AuthorORCID
Bjorkman, Pamela J.0000-0002-2277-3990
Additional Information:© 1996 Cell Press. We thank Yvonne Jones and Lawrence Shapiro for providing coordinates of VCAM-1 and N-cadherin domain 1; Andrew Huber, Harold Erickson, and Allan Bieber for communicating results prior to publication; Arthur Chirino for help with figures; and Andrew Huber, Robert Lane, Henry Lester, Paul Patterson, Luis Sanchez, Jost Vielmetter, William Weis, and Kai Zinn for critical reading of the manuscript. Support was provided by a National Institutes of Health predoctoral fellowship (D. E. V.) and the Howard Hughes Medical Institute (P. J. B.).
Funders:
Funding AgencyGrant Number
NIH Predoctoral FellowshipUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:2
DOI:10.1016/S0896-6273(00)80045-8
Record Number:CaltechAUTHORS:20170406-101209862
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170406-101209862
Official Citation:Daniel E Vaughn, Pamela J Bjorkman, The (Greek) Key to Structures of Neural Adhesion Molecules, Neuron, Volume 16, Issue 2, February 1996, Pages 261-273, ISSN 0896-6273, http://dx.doi.org/10.1016/S0896-6273(00)80045-8. (http://www.sciencedirect.com/science/article/pii/S0896627300800458)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:75795
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:06 Apr 2017 17:58
Last Modified:15 Nov 2021 16:36

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