CaltechAUTHORS
  A Caltech Library Service

Cavitation Bubble Cluster Activity in the Breakage of Kidney Stones by Lithotripter Shock Waves

Pishchalnikov, Yuriy A. and Sapozhnikov, Oleg A. and Bailey, Michael R. and Williams, James C., Jr. and Cleveland, Robin O. and Colonius, Tim and Crum, Lawrence A. and Evan, Andrew P. and McAteer, James A. (2003) Cavitation Bubble Cluster Activity in the Breakage of Kidney Stones by Lithotripter Shock Waves. Journal of Endourology, 17 (7). pp. 435-446. ISSN 1557-900X. PMCID PMC2442573. https://resolver.caltech.edu/CaltechAUTHORS:20170409-075315005

[img] PDF - Accepted Version
See Usage Policy.

4Mb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20170409-075315005

Abstract

Background and Purpose: There is strong evidence that cavitation bubble activity contributes to stone breakage and that shockwave-bubble interactions are involved in the tissue trauma associated with shockwave lithotripsy. Cavitation control may thus be a way to improve lithotripsy. Materials and Methods: High-speed photography was used to analyze cavitation bubble activity at the surface of artificial and natural kidney stones during exposure to lithotripter shockwaves in vitro. Results: Numerous individual bubbles formed on the surfaces of stones, but these bubbles did not remain independent but rather combined to form clusters. Bubble clusters formed at the proximal and distal ends and at the sides of stones. Each cluster collapsed to a narrow point of impact. Collapse of the proximal cluster eroded the leading face of the stone, and the collapse of clusters at the sides of stones appeared to contribute to the growth of cracks. Collapse of the distal cluster caused minimal damage. Conclusion: Cavitation-mediated damage to stones is attributable, not to the action of solitary bubbles, but to the growth and collapse of bubble clusters.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1089/089277903769013568DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442573/PubMed CentralArticle
ORCID:
AuthorORCID
Colonius, Tim0000-0003-0326-3909
Additional Information:© 2003 Mary Ann Liebert. This research was supported by NIH grants DK43881 and DK55674 and by a grant from the Whitaker Foundation.
Funders:
Funding AgencyGrant Number
NIHDK43881
NIHDK55674
Whitaker FoundationUNSPECIFIED
Issue or Number:7
PubMed Central ID:PMC2442573
Record Number:CaltechAUTHORS:20170409-075315005
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170409-075315005
Official Citation:Pishchalnikov YA, Sapozhnikov OA, Bailey MR, et al. Cavitation Bubble Cluster Activity in the Breakage of Kidney Stones by Lithotripter Shock Waves. Journal of endourology / Endourological Society. 2003;17(7):435-446. doi:10.1089/089277903769013568.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:76444
Collection:CaltechAUTHORS
Deposited By: 1Science Import
Deposited On:03 Apr 2018 22:07
Last Modified:03 Oct 2019 17:01

Repository Staff Only: item control page