A Caltech Library Service

Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves

Kartalov, Emil P. and Scherer, Axel and Quake, Stephen R. and Taylor, Clive R. and Anderson, W. French (2007) Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves. Journal of Applied Physics, 101 (6). Art. No. 064505. ISSN 0021-8979. doi:10.1063/1.2511688.

See Usage Policy.


Use this Persistent URL to link to this item:


A systematic experimental study and theoretical modeling of the device physics of polydimethylsiloxane “pushdown” microfluidic valves are presented. The phase space is charted by 1587 dimension combinations and encompasses 45–295 µm lateral dimensions, 16–39 µm membrane thickness, and 1–28 psi closing pressure. Three linear models are developed and tested against the empirical data, and then combined into a fourth-power-polynomial superposition. The experimentally validated final model offers a useful quantitative prediction for a valve's properties as a function of its dimensions. Typical valves (80–150 µm width) are shown to behave like thin springs.

Item Type:Article
Related URLs:
URLURL TypeDescription
Additional Information:©2007 American Institute of Physics. (Received 22 June 2006; accepted 29 December 2006; published online 19 March 2007) The authors thank Alejandro Meruelo and Daniel O’Hanlon from Caltech for their help with preliminary steps, and Alejandra Torres, Christina Morales, and Ali Ghaffari of the Caltech Micro/Nano-Fluidic Foundry for their help with device fabrication. Financial support for this work was provided by the NIH 1RO1 HG002644-01A1 and NIH 1 K99EB007151-01.
Subject Keywords:elastomers; microfluidics; microvalves
Issue or Number:6
Record Number:CaltechAUTHORS:KARjap07
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:7663
Deposited By: Archive Administrator
Deposited On:21 Mar 2007
Last Modified:08 Nov 2021 20:44

Repository Staff Only: item control page