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Evidence for a ring structure of polyoma virus DNA

Dulbecco, R. and Vogt, M. (1963) Evidence for a ring structure of polyoma virus DNA. Proceedings of the National Academy of Sciences of the United States of America, 50 (2). pp. 236-243. ISSN 0027-8424. PMCID PMC221161. doi:10.1073/pnas.50.2.236.

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The DNA of polyoma (PY) virus has two interesting features: it is unusually resistant to heat or formamide denaturation,(1) and it has two distinct components, of sedimentation coefficient 14 and 21, respectively.(2) A two-component sedimentation was formerly shown to be a characteristic of the DNA of papilloma virus,(3) which is considered a member of the same group of viruses.

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Additional Information:© 1963 by the National Academy of Sciences. Communicated June 11, 1963. We are grateful to Prof. R.L. Sinsheimer for useful discussions. The competent and dedicated assistance of Miss Maureen Muir is gratefully acknowledged. This work will be supplemented by studies with the analytical ultracentrifuge.(17) Aided by grants from the National Institutes of Health, U.S. Public Health Service, the American Cancer Society, and The National Foundation.
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American Cancer SocietyUNSPECIFIED
National Foundation for Infantile ParalysisUNSPECIFIED
Issue or Number:2
PubMed Central ID:PMC221161
Record Number:CaltechAUTHORS:DULpnas63
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:7673
Deposited By: Tony Diaz
Deposited On:21 Mar 2007
Last Modified:01 Jun 2023 23:14

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