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Potentiometric Saccharide Detection Based on the pK_a Changes of Poly(aniline boronic acid)

Shoji, Eiichi and Freund, Michael S. (2002) Potentiometric Saccharide Detection Based on the pK_a Changes of Poly(aniline boronic acid). Journal of the American Chemical Society, 124 (42). pp. 12486-12493. ISSN 0002-7863. doi:10.1021/ja0267371. https://resolver.caltech.edu/CaltechAUTHORS:20170427-102110510

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Abstract

A novel approach for the potentiometric detection of saccharides using poly(aniline boronic acid) is presented. A model is described in which the electrochemical potential is sensitive to the change in the pK_a of the conducting polymer as a result of boronic acid−diol complexation. In this system, boronic acid complexation is the mode of transduction and it is manifested as changes in the electrochemical potential of the polymer with remarkable selectivity. Characteristics of both transient and steady-state response associated with the complexation are discussed. The presence of Nafion and fluoride during the electrochemical polymerization of 3-aminophenylboronic acid are shown to impact the sensitivity and the stability of the electrode response. The sensor sensitivity is improved significantly by increasing the concentration of sodium fluoride during the polymerization. Finally, the nature of the selectivity of the boronic acid−diol reaction under these conditions is explored by using molecular orbital calculations.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1021/ja0267371DOIArticle
http://pubs.acs.org/doi/abs/10.1021/ja0267371PublisherArticle
ORCID:
AuthorORCID
Freund, Michael S.0000-0003-1104-2292
Additional Information:© 2002 American Chemical Society. Received April 30, 2002. Publication Date (Web): September 28, 2002. This work was supported by the Arnold and Mabel Beckman Foundation.
Funders:
Funding AgencyGrant Number
Arnold and Mabel Beckman FoundationUNSPECIFIED
Issue or Number:42
DOI:10.1021/ja0267371
Record Number:CaltechAUTHORS:20170427-102110510
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170427-102110510
Official Citation:Potentiometric Saccharide Detection Based on the pKa Changes of Poly(aniline boronic acid) Eiichi Shoji and Michael S. Freund Journal of the American Chemical Society 2002 124 (42), 12486-12493 DOI: 10.1021/ja0267371
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:76997
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:27 Apr 2017 17:26
Last Modified:15 Nov 2021 17:04

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