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Polymer-Based nanoparticle therapeutics

Davis, Mark E. (2017) Polymer-Based nanoparticle therapeutics. In: 253rd American Chemical Society National Meeting & Exposition, April 2-6, 2017, San Francisco, CA.

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We have translated three polymer-based nanoparticles into the clinic for use as cancer therapeutics. One of these nanoparticle, exptl. therapeutics was the first to show functional RNA interference (RNAi) in humans. At this time, these nanoparticles have been investigated in over 10 different clin. trials. I will describe how we translated these nanoparticles from the lab. at Caltech into clin., exptl. therapeutics. In addn. to investigations of polymer-based nanoparticle therapeutics for cancer, we are now concg. on developing polymer-based nanoparticles that cross the blood-brain-barrier. Our recent efforts will be presented.

Item Type:Conference or Workshop Item (Paper)
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Davis, Mark E.0000-0001-8294-1477
Additional Information:© 2017 American Chemical Society.
Record Number:CaltechAUTHORS:20170502-102605956
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:77123
Deposited By: Tony Diaz
Deposited On:02 May 2017 17:49
Last Modified:09 Mar 2020 13:18

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