A Fischer Indolization Strategy toward the Total Synthesis of (–)-Goniomitine

Pritchett, Beau P. and Kikuchi, Jun and Numajiri, Yoshitaka and Stoltz, Brian M. (2017) A Fischer Indolization Strategy toward the Total Synthesis of (–)-Goniomitine. Heterocycles, 95 (2). pp. 1245-1253. ISSN 0385-5414. PMCID PMC5502790. doi:10.3987/COM-16-S(S)80. https://resolver.caltech.edu/CaltechAUTHORS:20170706-132827697

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Abstract

A Fischer indolization strategy toward the core of (–)-goniomitine is reported. Initial investigations into the Pd-catalyzed asymmetric allylic alkylation of dihydropyrido[1,2-a]indolone (DHPI) substrates are also discussed.

Item Type:

Article

Related URLs:

URL	URL Type	Description
https://doi.org/10.3987/COM-16-S(S)80	DOI	Article
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502790	PubMed Central	Article

ORCID:

Author	ORCID
Pritchett, Beau P.	0000-0001-9922-9160
Stoltz, Brian M.	0000-0001-9837-1528

Additional Information:

© 2017 The Japan Institute of Heterocyclic Chemistry. Published online: 15th February, 2017. The authors wish to thank NIH-NIGMS (R01GM080269), Amgen, the Gordon and Betty Moore Foundation, and Caltech for financial support. B.P.P. thanks the NSF for a predoctoral fellowship (Grant DGE-1144469). Y. N. thanks Toray Industries Inc. for a postdoctoral fellowship. The authors thank Dr. Scott Virgil (Caltech) and the Caltech Center for Catalysis and Chemical Synthesis, for instrumentation assistance. Katerina Korch is acknowledged for experimental assistance.

Funders:

Funding Agency	Grant Number
NIH	R01GM080269
Amgen	UNSPECIFIED
Gordon and Betty Moore Foundation	UNSPECIFIED
Caltech	UNSPECIFIED
NSF Graduate Research Fellowship	DGE-1144469
Toray Industries Inc.	UNSPECIFIED

Issue or Number:

PubMed Central ID:

PMC5502790

DOI:

10.3987/COM-16-S(S)80

Record Number:

CaltechAUTHORS:20170706-132827697

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20170706-132827697

Usage Policy:

No commercial reproduction, distribution, display or performance rights in this work are provided.

ID Code:

78814

Collection:

CaltechAUTHORS

Deposited By:

Tony Diaz

Deposited On:

06 Jul 2017 21:17

Last Modified:

05 Apr 2022 17:39

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