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PIWIL4 Acts as a piRNA Binding, Epigenetically Active and Growth Regulatory Protein in Human Acute Myeloid Leukemia

Bamezai, S. and Mulaw, M. and Vegi, N. and Feuring-Buske, M. and Zhou, F. and Rohde, C. and Aravin, A. and Hoell, J. and Kloetgen, A. and Borkhardt, A. and Plass, C. and Müller-Tidow, C. and Rawat, V. P. and Buske, C. (2017) PIWIL4 Acts as a piRNA Binding, Epigenetically Active and Growth Regulatory Protein in Human Acute Myeloid Leukemia. Haematologica, 102 (S2). Art. No. S429. ISSN 0390-6078. https://resolver.caltech.edu/CaltechAUTHORS:20170714-085839589

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Abstract

Piwi proteins are critically important for maintaining the self-renewing stem cell population in lower organisms through epigenetic silencing of transposable elements via DNA methylation and H3K9me3 marks, in close interaction with a novel class of non-coding RNA called piwi interacting RNA (piRNA).


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.haematologica.org/content/102/s2/1.full.pdf+htmlPublisherAbstracts
Additional Information:© 2017 by the Ferrata Storti Foundation.
Issue or Number:S2
Record Number:CaltechAUTHORS:20170714-085839589
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170714-085839589
Official Citation:22nd Congress of the European Hematology Association Madrid, Spain, June 22–25, 2017 Haematologica Jun 2017, 102 (s2) 1-882
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:79106
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:14 Jul 2017 16:11
Last Modified:03 Oct 2019 18:16

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