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Idiothetic Path Integration in the Fruit Fly Drosophila melanogaster

Kim, Irene S. and Dickinson, Michael H. (2017) Idiothetic Path Integration in the Fruit Fly Drosophila melanogaster. Current Biology, 27 (15). pp. 2227-2238. ISSN 0960-9822. https://resolver.caltech.edu/CaltechAUTHORS:20170725-092327425

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Abstract

After discovering a small drop of food, hungry flies exhibit a peculiar behavior in which they repeatedly stray from, but then return to, the newly discovered resource. To study this behavior in more detail, we tracked hungry Drosophila as they explored a large arena, focusing on the question of how flies remain near the food. To determine whether flies use external stimuli, we individually eliminated visual, olfactory, and pheromonal cues. In all cases, flies still exhibited a centralized search behavior, suggesting that none of these cues are absolutely required for navigation back to the food. To simultaneously eliminate visual and olfactory cues associated with the position of the food, we constructed an apparatus in which the food could be rapidly translated from the center of the arena. Flies continued to search around the original location, even after the food was moved to a new position. A random search model based on measured locomotor statistics could not reproduce the centered nature of the animal’s trajectory. We conclude that this behavior is best explained by a form of path integration in which the flies use idiothetic cues to search near the location of the food. We argue that the use of path integration to perform a centered local search is not a specialization of Drosophila but rather represents an ancient behavioral mode that is homologous to the more elaborate foraging strategies of central place foragers such as ants.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/j.cub.2017.06.026DOIArticle
http://www.sciencedirect.com/science/article/pii/S0960982217307285PublisherArticle
ORCID:
AuthorORCID
Dickinson, Michael H.0000-0002-8587-9936
Additional Information:© 2017 Elsevier Ltd. Received 18 April 2017, Revised 26 May 2017, Accepted 9 June 2017, Available online 20 July 2017. Published: July 20, 2017. We wish to thank Christie Huang for help with conducting these experiments, and Steve Safarik for developing our tracking software. Joel Levine kindly provided us with flies. John Tuthill, Rachel Wilson, Pavan Ramdya, and Paul Graham provided valuable feedback on this manuscript. This work was supported by the Human Frontiers of Science Program (grant RGP0022/2012) and National Institute of Neurological Disorders and Stroke of the NIH (award U01NS090514). Author Contributions: Conceptualization, I.S.K. and M.H.D.; Methodology, I.S.K. and M.H.D.; Investigation, I.S.K.; Formal Analysis, I.S.K.; Writing, I.S.K. and M.H.D.; Funding Acquisition, M.H.D.; Supervision, M.H.D.
Funders:
Funding AgencyGrant Number
Human Frontier Science ProgramRGP0022/2012
NIHU01NS090514
Subject Keywords:path integration; Drosophila; navigation; local search; foraging
Issue or Number:15
Record Number:CaltechAUTHORS:20170725-092327425
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170725-092327425
Official Citation:Irene S. Kim, Michael H. Dickinson, Idiothetic Path Integration in the Fruit Fly Drosophila melanogaster, Current Biology, Volume 27, Issue 15, 7 August 2017, Pages 2227-2238.e3, ISSN 0960-9822, https://doi.org/10.1016/j.cub.2017.06.026. (http://www.sciencedirect.com/science/article/pii/S0960982217307285)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:79324
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:25 Jul 2017 16:33
Last Modified:03 Oct 2019 18:18

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