CaltechAUTHORS
  A Caltech Library Service

Statistical Analysis of the Additive and Multiplicative Hypotheses of Multiple Exposure Synergy for Cohort and Case-Control Studies

Dubin, Jeffrey A. (1999) Statistical Analysis of the Additive and Multiplicative Hypotheses of Multiple Exposure Synergy for Cohort and Case-Control Studies. Social Science Working Paper, 1066. California Institute of Technology , Pasadena, CA. (Unpublished) https://resolver.caltech.edu/CaltechAUTHORS:20170810-152247165

[img] PDF (sswp 1066 - Jul. 1999) - Submitted Version
See Usage Policy.

298Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20170810-152247165

Abstract

This paper considers hypotheses tests for synergistic relationships in epidemiological studies. Two hypotheses are considered. First, I develop tests of the additive hypothesis which states that the combined risk from two sources of exposure is the sum of each risk taken separately. I then develop tests for the hypothesis that a multiplicative relationship exists for the risks, i.e., that the combined risk is consistent with the multiplication of the individual risks. Following standard practice in epidemiological studies I consider tests for both case-referent and cohort (standardized mortality rate) type studies.


Item Type:Report or Paper (Working Paper)
Related URLs:
URLURL TypeDescription
http://resolver.caltech.edu/CaltechAUTHORS:20170816-145820663Related ItemPublished Version
Additional Information:Published as Dubin, J. A. (2001). Statistical Analysis of the Additive and Multiplicative Hypotheses of Multiple Exposure Synergy for Cohort and Case-Control Studies. In Empirical Studies in Applied Economics (pp. 87-116). Springer US.
Group:Social Science Working Papers
Subject Keywords:synergy, cohort, case-control, epidemiology
Series Name:Social Science Working Paper
Issue or Number:1066
Record Number:CaltechAUTHORS:20170810-152247165
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170810-152247165
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:80253
Collection:CaltechAUTHORS
Deposited By: Jacquelyn Bussone
Deposited On:10 Aug 2017 22:32
Last Modified:03 Oct 2019 18:28

Repository Staff Only: item control page