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Rules of the road for insect gene drive research and testing

Adelman, Zach and Hay, Bruce A. (2017) Rules of the road for insect gene drive research and testing. Nature Biotechnology, 35 (8). pp. 716-718. ISSN 1087-0156. PMCID PMC5831321. doi:10.1038/nbt.3926. https://resolver.caltech.edu/CaltechAUTHORS:20170814-130030897

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Abstract

Approximately two years ago, two of us (E.B. and V.G.) demonstrated the first experimental application of CRISPR–Cas9 to 'drive' a desired trait throughout a population of fruit flies. In November 2015, this same team at the University of California, San Diego, joined with A.A.J. and others at the University of California, Irvine, to develop a CRISPR-based gene drive for population modification of the malaria vector mosquito Anopheles stephensi. A month later, a group in the United Kingdom applied a CRISPR-based gene drive to another malaria vector, Anopheles gambiae.


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https://doi.org/10.1038/nbt.3926DOIArticle
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831321PubMed CentralArticle
Additional Information:© 2017 Nature America, Inc. Published online 08 August 2017. This Correspondence represents the views of the authors only, and not necessarily those of the entities with which they are affiliated. The authors declare competing financial interests: details are available in the online version of the paper.
Issue or Number:8
PubMed Central ID:PMC5831321
DOI:10.1038/nbt.3926
Record Number:CaltechAUTHORS:20170814-130030897
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170814-130030897
Official Citation:Adelman, Z., Akbari, O., Bauer, J. et al. Rules of the road for insect gene drive research and testing. Nat Biotechnol 35, 716–718 (2017). https://doi.org/10.1038/nbt.3926
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:80359
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:14 Aug 2017 22:21
Last Modified:15 Nov 2021 19:30

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