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Separable Bilayer Microfiltration Device for Label-Free Enrichment of Viable Circulating Tumor Cells

Hao, Sijie and Nisic, Merisa and He, Hongzhang and Tai, Yu-Chong and Zheng, Si-Yang (2017) Separable Bilayer Microfiltration Device for Label-Free Enrichment of Viable Circulating Tumor Cells. In: Circulating Tumor Cells. Methods in Molecular Biology. No.1634. Humana Press , New York, NY, pp. 81-91. ISBN 978-1-4939-7143-5. http://resolver.caltech.edu/CaltechAUTHORS:20170821-085135191

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Abstract

Analysis of rare circulating tumor cells enriched from metastatic cancer patients yields critical information on disease progression, therapy response, and the mechanism of cancer metastasis. Here we describe in detail a label-free enrichment process of circulating tumor cells based on its unique physical properties (size and deformability). Viable circulating tumor cells can be successfully enriched and analyzed, or easily released for further characterization due to the novel separable two-layer design.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1007/978-1-4939-7144-2_6DOIArticle
https://link.springer.com/protocol/10.1007/978-1-4939-7144-2_6PublisherArticle
ORCID:
AuthorORCID
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 2017 Springer Science+Business Media LLC. First Online: 18 August 2017.
Subject Keywords:Circulating tumor cells; Viable CTC isolation; Cancer metastasis; CTC in vitro culture; Microfabrication
Record Number:CaltechAUTHORS:20170821-085135191
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20170821-085135191
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:80638
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:21 Aug 2017 16:17
Last Modified:21 Aug 2017 16:17

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