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Dorsal Premotor Neurons Encode the Relative Position of the Hand, Eye, and Goal during Reach Planning

Pesaran, Bijan and Nelson, Matthew J. and Andersen, Richard A. (2006) Dorsal Premotor Neurons Encode the Relative Position of the Hand, Eye, and Goal during Reach Planning. Neuron, 51 (1). pp. 125-134. ISSN 0896-6273. PMCID PMC3066049. https://resolver.caltech.edu/CaltechAUTHORS:20170823-133847993

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Abstract

When reaching to grasp an object, we often move our arm and orient our gaze together. How are these movements coordinated? To investigate this question, we studied neuronal activity in the dorsal premotor area (PMd) and the medial intraparietal area (area MIP) of two monkeys while systematically varying the starting position of the hand and eye during reaching. PMd neurons encoded the relative position of the target, hand, and eye. MIP neurons encoded target location with respect to the eye only. These results indicate that whereas MIP encodes target locations in an eyecentered reference frame, PMd uses a relative position code that specifies the differences in locations between all three variables. Such a relative position code may play an important role in coordinating hand and eye movements by computing their relative position.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/j.neuron.2006.05.025DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066049/PubMed CentralArticle
ORCID:
AuthorORCID
Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 2006 Elsevier Inc. Received 25 October 2005, Revised 31 March 2006, Accepted 26 May 2006, Available online 5 July 2006. Published: July 5, 2006. We would like to acknowledge valuable conversations with Chris Buneo and helpful comments on the manuscript from Alex Gail and Sam Musallam. This work was supported by NIH grants EY05522-21 and MH62528-01, the DARPA BioInfoMicro program, and a Career Award in the Biomedical Sciences from the Burroughs Wellcome Fund to B.P. We thank Tessa Yao for editorial assistance, Kelsie Pejsa and Leah Martel for animal care, and Viktor Shcherbatyuk for technical assistance.
Funders:
Funding AgencyGrant Number
NIHEY05522-21
NIHMH62528-01
Defense Advanced Research Projects Agency (DARPA)UNSPECIFIED
Burroughs Wellcome FundUNSPECIFIED
Issue or Number:1
PubMed Central ID:PMC3066049
Record Number:CaltechAUTHORS:20170823-133847993
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20170823-133847993
Official Citation:Bijan Pesaran, Matthew J. Nelson, Richard A. Andersen, Dorsal Premotor Neurons Encode the Relative Position of the Hand, Eye, and Goal during Reach Planning, Neuron, Volume 51, Issue 1, 2006, Pages 125-134, ISSN 0896-6273, http://dx.doi.org/10.1016/j.neuron.2006.05.025. (http://www.sciencedirect.com/science/article/pii/S0896627306004181)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:80734
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:24 Aug 2017 23:30
Last Modified:31 Mar 2020 20:53

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