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Imidazo bibyclic imminium compounds as antitumor agents

Chen, James and Kato, Tomoyo Sakata and Ondrus, Alison Evelynn (2014) Imidazo bibyclic imminium compounds as antitumor agents. Patent number: US9611276B2.

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The invention relates to imidazobicycles having a quaternary nitrogen that are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.

Item Type:Patent
Related Patents:US20150191489A1
Patent Classification:A61K 31/4188, A61K 31/437, A61 K 31/5383, C07D 471/04, C07D 498/04, A61K 31/429, A61K 31/55, C07D 487/04, C07D 513/04, A61P 35/00
Patent Assignee:The Board of Trustees of the Leland Stanford Junior University
Related URLs:
URLURL TypeDescription Patents Patent Office Application
Ondrus, Alison Evelynn0000-0002-6023-3290
Additional Information:Appl. No.: 14/409,683 Filed: June 19, 2013 PCT Filed: June 19, 2013 PCT No.: PCT/US2013/046560 371(c)(1),(2),(4) Date: December 19, 2014 PCT Pub. No.: WO2013/192301 PCT Pub. Date: December 27, 2013. Government Interests: This invention was made with Government support under contract CA136574 awarded by the National Institutes of Health. The Government has certain rights in this invention. Parent Case Text: This application is a national phase filing under 35 U.S.C. .sctn.371 of PCT International Application PCT/US2013/046560, filed Jun. 19, 2013, and published under PCT Article 21(2) as WO 2013/192301 on Dec. 27, 2013. PCT/US2013/046560 claims priority from U.S. provisional application 61/662,977, filed Jun. 22, 2012. The contents of each of the prior applications are incorporated herein by reference in their entirety.
Funding AgencyGrant Number
Record Number:CaltechAUTHORS:20170901-135026964
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:81083
Deposited By: Donna Wrublewski
Deposited On:21 Sep 2017 22:54
Last Modified:25 Apr 2022 20:48

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