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Imidazo bibyclic imminium compounds as antitumor agents

Chen, James and Kato, Tomoyo Sakata and Ondrus, Alison Evelynn (2014) Imidazo bibyclic imminium compounds as antitumor agents. Patent number: US9611276B2. http://resolver.caltech.edu/CaltechAUTHORS:20170901-135026964

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Abstract

The invention relates to imidazobicycles having a quaternary nitrogen that are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.


Item Type:Patent
Related Patents:US20150191489A1
Patent Classification:A61K 31/4188, A61K 31/437, A61 K 31/5383, C07D 471/04, C07D 498/04, A61K 31/429, A61K 31/55, C07D 487/04, C07D 513/04, A61P 35/00
Patent Assignee:The Board of Trustees of the Leland Stanford Junior University
Related URLs:
URLURL TypeDescription
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=%22US+9611276%22&OS=PatentUSPTO
https://www.google.com/patents/US9611276PatentGoogle Patents
https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161228&DB=&locale=en_EP&CC=EP&NR=2864332B1&KC=B1&ND=5PatentEuropean Patent Office
https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131227&DB=&locale=en_EP&CC=WO&NR=2013192301A1&KC=A1&ND=7PatentPCT Application
Additional Information:Appl. No.: 14/409,683 Filed: June 19, 2013 PCT Filed: June 19, 2013 PCT No.: PCT/US2013/046560 371(c)(1),(2),(4) Date: December 19, 2014 PCT Pub. No.: WO2013/192301 PCT Pub. Date: December 27, 2013. Government Interests: This invention was made with Government support under contract CA136574 awarded by the National Institutes of Health. The Government has certain rights in this invention. Parent Case Text: This application is a national phase filing under 35 U.S.C. .sctn.371 of PCT International Application PCT/US2013/046560, filed Jun. 19, 2013, and published under PCT Article 21(2) as WO 2013/192301 on Dec. 27, 2013. PCT/US2013/046560 claims priority from U.S. provisional application 61/662,977, filed Jun. 22, 2012. The contents of each of the prior applications are incorporated herein by reference in their entirety.
Funders:
Funding AgencyGrant Number
NIHCA136574
Record Number:CaltechAUTHORS:20170901-135026964
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20170901-135026964
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:81083
Collection:CaltechAUTHORS
Deposited By: Donna Wrublewski
Deposited On:21 Sep 2017 22:54
Last Modified:21 Sep 2017 23:05

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