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Volatile nematode sex pheromones

Shinya, Ryoji and Gronquist, Mathew and Leighton, Daniel H. W. and Hsueh, Yen-Ping and Schroeder, Frank and Sternberg, Paul (2017) Volatile nematode sex pheromones. In: 254th American Chemical Society National Meeting & Exposition, 20-24 August 2017, Washington, DC.

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Nematodes produce a staggering array of sol. social cues, glycosides of dideoxy-sugars such as the ascarylose (ascarosides), that are secondary metabolites and communicate information such as population d. and location of sex partners. We found that predatory fungi respond to certain ascarosides by making sticky traps that trap and kill nematodes. This finding suggested that one driver of the evolution of ascaroside prodn. is avoiding predation. We have recently identified using GC-MS of the head-space of cultures of two distant genera of nematodes - the fungal-feeding and tree-parasitic Bursaphelenchus and the fruit-assocd., free-living Caenorhabditis - a set of volatile compds. that are produced by nematodes and attract sex partners. These compds. are hexenyl acetates and relatives. The prodn. of, and response to, these volatiles are genus specific, suggesting that the volatile pheromones might be under similar selective pressures as the sol. pheromones. Indeed, the same predatory fungi that senses ascarosides as a proxy for nematodes attract nematodes by prodn. of volatile org. compds. One of these, methyl-2 methyl-3 butenoate, is a potent attractor of hermaphrodite (female) nematodes but not males, suggesting that it mimics endogenous volatile pheromones. The prodn. of volatile pheromones by females is regulated by their sperm status: only unmated females produce the pheromone, suggesting a way to identify candidate genes that control pheromone prodn.

Item Type:Conference or Workshop Item (Paper)
Related URLs:
URLURL TypeDescription Website
Leighton, Daniel H. W.0000-0002-1379-0078
Schroeder, Frank0000-0002-4420-0237
Sternberg, Paul0000-0002-7699-0173
Additional Information:© 2017 American Chemical Society.
Record Number:CaltechAUTHORS:20170915-080841696
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:81478
Deposited By: Tony Diaz
Deposited On:15 Sep 2017 16:24
Last Modified:29 Oct 2019 20:53

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