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Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation

Yang, Jiamiao and Shen, Yuecheng and Liu, Yan and Hemphill, Ashton S. and Wang, Lihong V. (2017) Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation. Applied Physics Letters, 111 (20). Art. No. 201108. ISSN 0003-6951. PMCID PMC5690666. https://resolver.caltech.edu/CaltechAUTHORS:20171122-080140092

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Abstract

Optical scattering prevents light from being focused through thick biological tissue at depths greater than ∼1 mm. To break this optical diffusion limit, digital optical phase conjugation (DOPC) based wavefront shaping techniques are being actively developed. Previous DOPC systems employed spatial light modulators that modulated either the phase or the amplitude of the conjugate light field. Here, we achieve optical focusing through scattering media by using polarization modulation based generalized DOPC. First, we describe an algorithm to extract the polarization map from the measured scattered field. Then, we validate the algorithm through numerical simulations and find that the focusing contrast achieved by polarization modulation is similar to that achieved by phase modulation. Finally, we build a system using an inexpensive twisted nematic liquid crystal based spatial light modulator (SLM) and experimentally demonstrate light focusing through 3-mm thick chicken breast tissue. Since the polarization modulation based SLMs are widely used in displays and are having more and more pixel counts with the prevalence of 4 K displays, these SLMs are inexpensive and valuable devices for wavefront shaping.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1063/1.5005831DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690666/PubMed CentralArticle
ORCID:
AuthorORCID
Yang, Jiamiao0000-0003-0006-8411
Shen, Yuecheng0000-0003-1990-8142
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2017 Published by AIP Publishing. Received 19 September 2017; accepted 27 October 2017; published online 16 November 2017. This work was sponsored by NIH Grants Nos. DP1 EB016986 (NIH Director's Pioneer Award), R01 CA186567 (NIH Director's Transformative Research Award), and U01 NS090579 (BRAIN Initiative).
Funders:
Funding AgencyGrant Number
NIHDP1 EB016986
NIHR01 CA186567
NIHU01 NS090579
Subject Keywords:Wave mechanics; Optical modulators; Nematic liquid crystals; Optical scattering; Polarization
Issue or Number:20
PubMed Central ID:PMC5690666
Record Number:CaltechAUTHORS:20171122-080140092
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20171122-080140092
Official Citation:Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation. Jiamiao Yang, Yuecheng Shen, Yan Liu, Ashton S. Hemphill, and Lihong V. Wang. Applied Physics Letters 2017 111:20
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:83421
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:22 Nov 2017 17:11
Last Modified:03 Oct 2019 19:06

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