CaltechAUTHORS
  A Caltech Library Service

Black silicon as a multifunctional material for medical implants: First demonstrated use in in-vivo intraocular pressure sensing

Narasimhan, Vinayak and Lee, Jeong Oen and Du, Juan and Ndjamen, Blaise and Sretavan, David and Choo, Hyuck (2017) Black silicon as a multifunctional material for medical implants: First demonstrated use in in-vivo intraocular pressure sensing. In: 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS). IEEE , Piscataway, NJ, pp. 387-390. ISBN 978-1-5386-2732-7. https://resolver.caltech.edu/CaltechAUTHORS:20180105-095739798

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20180105-095739798

Abstract

We report the first in vivo demonstrated use of multifunctional black silicon (b-Si) on medical implants. B-Si is integrated onto the surface of a highly miniaturized sub-mm implantable intraocular pressure (IOP) sensor. This integration has significantly improved sensor signal-to-noise ratio (SNR) through the suppression of background noise as well as durability through minimized device biofouling. The incorporation of b-Si has enabled the use of a slit-lamp, the most widely used clinical ophthalmic microscope, for real-time IOP measurements on fully awake rabbits at a world-record 12-cm readout distance. Furthermore, b-Si has shown remarkable antifouling properties during a 6-month in vivo study by minimizing tissue proliferation and encapsulation on the ocular implant, promising much improved long-term implant serviceability.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/TRANSDUCERS.2017.7994068DOIArticle
http://ieeexplore.ieee.org/document/7994068/PublisherArticle
ORCID:
AuthorORCID
Choo, Hyuck0000-0002-8903-7939
Additional Information:© 2017 IEEE. This work was funded by the National Institute of Health (NIH) (Grant No. EY024582), HMRI Investigator Award, Caltech CI2, and Powell Foundation Award.
Group:Heritage Medical Research Institute
Funders:
Funding AgencyGrant Number
NIHEY024582
Heritage Medical Research InstituteUNSPECIFIED
Caltech Innovation Initiative (CI2)UNSPECIFIED
Charles Lee Powell FoundationUNSPECIFIED
Subject Keywords: Black silicon, multifunctional, glaucoma, intraocular pressure, implant, antifouling
Record Number:CaltechAUTHORS:20180105-095739798
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180105-095739798
Official Citation:V. Narasimhan, J. O. Lee, J. Du, B. Ndjamen, D. Sretavan and H. Choo, "Black silicon as a multifunctional material for medical implants: First demonstrated use in in-vivo intraocular pressure sensing," 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Kaohsiung, 2017, pp. 387-390. doi: 10.1109/TRANSDUCERS.2017.7994068 http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7994068&isnumber=7993963
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:84122
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:05 Jan 2018 21:19
Last Modified:03 Oct 2019 19:14

Repository Staff Only: item control page