Prober, David A. (2018) Discovery of Hypocretin/Orexin Ushers in a New Era of Sleep Research. Trends in Neurosciences, 41 (2). pp. 70-72. ISSN 0166-2236. PMCID PMC5805467. doi:10.1016/j.tins.2017.11.007. https://resolver.caltech.edu/CaltechAUTHORS:20180212-094508465
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Abstract
Prior to the 21st century, genetic mechanisms that regulate sleep were largely unknown. In 1998, de Lecea et al. [1] (Proc. Natl. Acad. Sci. U. S. A. 1998; 95:322–327) and Sakurai et al. [2] (Cell 1998; 92: 573–585) reported the discovery of a gene they named hypocretin and orexin, respectively, which led to a revolution in our understanding of genetic and neuronal mechanisms that regulate sleep.
Item Type: | Article | |||||||||
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Additional Information: | © 2017 Elsevier Ltd. Available online 6 February 2018. | |||||||||
Subject Keywords: | sleep; arousal; hypocretin; orexin | |||||||||
Issue or Number: | 2 | |||||||||
PubMed Central ID: | PMC5805467 | |||||||||
DOI: | 10.1016/j.tins.2017.11.007 | |||||||||
Record Number: | CaltechAUTHORS:20180212-094508465 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20180212-094508465 | |||||||||
Official Citation: | David A. Prober, Discovery of Hypocretin/Orexin Ushers in a New Era of Sleep Research, Trends in Neurosciences, Volume 41, Issue 2, February 2018, Pages 70-72, ISSN 0166-2236, https://doi.org/10.1016/j.tins.2017.11.007. (https://www.sciencedirect.com/science/article/pii/S0166223617302345) | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 84785 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | Ruth Sustaita | |||||||||
Deposited On: | 13 Feb 2018 18:52 | |||||||||
Last Modified: | 15 Nov 2021 20:22 |
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