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Emotional Attribution in High-Functioning Individuals With Autistic Spectrum Disorder: A Functional Imaging Study

Piggot, Judith and Kwon, Hower and Mobbs, Dean and Blasey, Christine and Lotspeich, Linda and Menon, Vinod and Bookheimer, Susan and Reiss, Allan L. (2004) Emotional Attribution in High-Functioning Individuals With Autistic Spectrum Disorder: A Functional Imaging Study. Journal of the American Academy of Child & Adolescent Psychiatry, 43 (4). pp. 473-480. ISSN 0890-8567. doi:10.1097/00004583-200404000-00014. https://resolver.caltech.edu/CaltechAUTHORS:20180305-092003625

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Abstract

Objective: To determine whether expertise in the attribution of emotion from basic facial expressions in high-functioning individuals with autistic spectrum disorder (ASD) is supported by the amygdala, fusiform, and prefrontal regions of interest (ROI) and is comparable to that of typically developing individuals. Method: Functional magnetic resonance imaging scans were acquired from 14 males with ASD and 10 matched adolescent controls while performing emotion match (EM) (perceptual), emotion label (EL) (linguistic), and control tasks. Accuracy, response time, and average activation were measured for each ROI. Results: There was no significant difference in accuracy, response time, or ROI activation between groups performing the EL task. The ASD group was as accurate as the control group performing the EM task but had a significantly longer response time and lower average fusiform activation. Conclusions: Expertise in the attribution of emotion from basic facial expressions was task-dependent in the high-functioning ASD group. The hypothesis that the high-functioning ASD group would be less expert and would have reduced fusiform activation was supported in the perceptual task but not the linguistic task. The reduced fusiform activation in the perceptual task was not explained by reduced expertise; it is therefore concluded that reduced fusiform activation is associated with the diagnosis of ASD.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1097/00004583-200404000-00014DOIArticle
https://www.sciencedirect.com/science/article/pii/S0890856709612545PublisherArticle
ORCID:
AuthorORCID
Mobbs, Dean0000-0003-1175-3772
Additional Information:© 2004 by the American Academy of Child and Adolescent Psychiatry. Accepted 7 October 2003. Financial support from M.I.N.D. Institute, NIH grants MH01142, MH50047, HD31715, MH64708, and a fellowship in basic research awarded to Dr. Piggot by the National Alliance of Autism Research. The authors thank Dr. Amy Garrett for help in manuscript preparation.
Funders:
Funding AgencyGrant Number
NIHMH01142
NIHMH50047
NIHHD31715
NIHMH64708
National Alliance of Autism ResearchUNSPECIFIED
Subject Keywords:autism spectrum disorders emotion functional magnetic resonance imaging
Issue or Number:4
DOI:10.1097/00004583-200404000-00014
Record Number:CaltechAUTHORS:20180305-092003625
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20180305-092003625
Official Citation:Judith Piggot, Hower Kwon, Dean Mobbs, Christine Blasey, Linda Lotspeich, Vinod Menon, Susan Bookheimer, Allan L. Reiss, Emotional Attribution in High-Functioning Individuals With Autistic Spectrum Disorder: A Functional Imaging Study, Journal of the American Academy of Child & Adolescent Psychiatry, Volume 43, Issue 4, 2004, Pages 473-480, ISSN 0890-8567, https://doi.org/10.1097/00004583-200404000-00014.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:85090
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:05 Mar 2018 22:40
Last Modified:15 Nov 2021 20:25

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