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Extinction as a deficit of the decision-making circuitry in the posterior parietal cortex

Christopoulos, Vassilios N. and Andersen, Kristen N. and Andersen, Richard A. (2018) Extinction as a deficit of the decision-making circuitry in the posterior parietal cortex. In: The Parietal Lobe. Handbook of Clinical Neurology. Vol.151. Elsevier , Amsterdam, pp. 163-182. ISBN 9780444636225. http://resolver.caltech.edu/CaltechAUTHORS:20180312-075808946

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Abstract

Extinction is a common neurologic deficit that often occurs as one of a constellation of symptoms seen with lesions of the posterior parietal cortex (PPC). Although extinction has typically been considered a deficit in the allocation of attention, new findings, particularly from nonhuman primate studies, point to one potential and important source of extinction as damage to decision-making circuits for actions within the PPC. This new understanding provides clues to potential therapies for extinction. Also the finding that the PPC is important for action decisions and action planning has led to new neuroprosthetic applications using PPC recordings as control signals to assist paralyzed patients.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/B978-0-444-63622-5.00008-5DOIArticle
https://www.sciencedirect.com/science/article/pii/B9780444636225000085PublisherArticle
Additional Information:© 2018 Elsevier B.V. Available online 6 March 2018.
Subject Keywords:visual extinction; visual neglect; posterior parietal cortex; decision making; brain–machine interface; neural rehabilitation; reach; saccade
Record Number:CaltechAUTHORS:20180312-075808946
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20180312-075808946
Official Citation:Vassilios N. Christopoulos, Kristen N. Andersen, Richard A. Andersen, Chapter 8 - Extinction as a deficit of the decision-making circuitry in the posterior parietal cortex, In: Giuseppe Vallar and H. Branch Coslett, Editor(s), Handbook of Clinical Neurology, Elsevier, 2018, Volume 151, Pages 163-182, ISSN 0072-9752, ISBN 9780444636225, https://doi.org/10.1016/B978-0-444-63622-5.00008-5. (https://www.sciencedirect.com/science/article/pii/B9780444636225000085)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:85237
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Mar 2018 17:28
Last Modified:12 Mar 2018 17:28

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