Cook, Colin A. and Martinez-Camarillo, Juan C. and Humayun, Mark S. and Tai, Yu-Chong (2017) Implantable phototherapy device to treat diabetic retinopathy. In: 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS). IEEE , Piscataway, NJ, pp. 393-396. ISBN 978-1-5386-2732-7. https://resolver.caltech.edu/CaltechAUTHORS:20180322-102107647
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20180322-102107647
Abstract
This paper reports on the first implantable phototherapy device to treat diabetic retinopathy by modulating rod cell metabolism through reduction of dark current. Utilizing a tritium-based radioluminescent light source capable of emitting around 505nm, the device achieves phototherapeutic activity for up to a 12-year service lifetime and <30mm^3 size. The unique scleral anchoring system facilitates simple, rapid, and robust implantation into the eye. Implantation into a rabbit model demonstrated safety over a 4-week period with no adverse effects observed.
| Item Type: | Book Section | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Related URLs: |
| |||||||||
| ORCID: |
| |||||||||
| Additional Information: | © 2017 IEEE. Thanks to the Caltech MEMS Lab members for their guidance with techniques and fabrication. Graduate scholarship provided by Natural Sciences and Engineering Research Council of Canada. | |||||||||
| Funders: |
| |||||||||
| DOI: | 10.1109/TRANSDUCERS.2017.7994070 | |||||||||
| Record Number: | CaltechAUTHORS:20180322-102107647 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20180322-102107647 | |||||||||
| Official Citation: | C. A. Cook, J. C. Martinez-Camarillo, M. S. Humayun and Y. C. Tai, "Implantable phototherapy device to treat diabetic retinopathy," 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Kaohsiung, 2017, pp. 393-396. doi: 10.1109/TRANSDUCERS.2017.7994070 URL: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7994070&isnumber=7993963 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 85414 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Tony Diaz | |||||||||
| Deposited On: | 26 Mar 2018 21:21 | |||||||||
| Last Modified: | 15 Nov 2021 20:28 |
Repository Staff Only: item control page
