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Nuclear Import: HIV-1 Goes NUPs

Woodward, Cora L. and Wu, Jonathan and Chow, Samson A. (2018) Nuclear Import: HIV-1 Goes NUPs. In: Encyclopedia of AIDS. Springer , New York, NY, pp. 1573-1581. ISBN 978-1-4939-7100-8.

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A key feature of human immunodeficiency virus type 1 (HIV-1) and other lentiviruses is their ability to traverse an intact nuclear envelope and productively infect nondividing cells. The nuclear import mechanisms of HIV-1 appear to involve interactions with several nucleoporin members, the constituent building blocks of nuclear pore complexes that span across the nuclear envelope.

Item Type:Book Section
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Additional Information:© 2018 Springer Science+Business Media LLC. First Online: 10 March 2018.
Record Number:CaltechAUTHORS:20180329-103637037
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:85488
Deposited By: Tony Diaz
Deposited On:29 Mar 2018 19:49
Last Modified:03 Oct 2019 19:31

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