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A 0.3ppm dual-resonance transformer-based drift-cancelling reference-free magnetic sensor for biosensing applications

Sideris, Constantine and Porsandeh Khial, Parham and Ling, Bill and Hajimiri, Ali (2018) A 0.3ppm dual-resonance transformer-based drift-cancelling reference-free magnetic sensor for biosensing applications. In: 2018 IEEE International Solid - State Circuits Conference - (ISSCC). IEEE , Piscataway, NJ, pp. 190-192. ISBN 978-1-5090-4940-0. http://resolver.caltech.edu/CaltechAUTHORS:20180412-104241139

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Abstract

Cost-efficient, point-of-use diagnostics are critical for early disease detection. Traditionally, the majority of lab-based analysis equipment utilizes fluorescent markers for biodetection assays. However, magnetic-based labels have recently been shown to be promising alternatives to fluorescent tags for DNA, protein, and cell assays. Magnetic assays offer several key advantages over their fluorescent counterparts, namely that magnetic beads do not suffer from signal decay due to bleaching and that they can be detected with cheap CMOS-based sensors, eliminating the need for expensive lasers, photo-diodes, filters, and complicated post-processing steps. Significant progress has recently been made in the design of magnetic imager ICs, such as [1] which utilizes a gMr approach for detection and [2-4] which measure the resonance shift in an LC tank.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1109/ISSCC.2018.8310248DOIArticle
https://ieeexplore.ieee.org/document/8310248PublisherArticle
ORCID:
AuthorORCID
Porsandeh Khial, Parham0000-0002-3242-8541
Additional Information:© 2018 IEEE. The authors thank K. Mauser and N. Scianmarello for help with sample preparation.
Record Number:CaltechAUTHORS:20180412-104241139
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20180412-104241139
Official Citation:C. Sideris, P. P. Khial, B. Ling and A. Hajimiri, "A 0.3ppm dual-resonance transformer-based drift-cancelling reference-free magnetic sensor for biosensing applications," 2018 IEEE International Solid - State Circuits Conference - (ISSCC), San Francisco, CA, 2018, pp. 190-192. doi: 10.1109/ISSCC.2018.8310248. URL: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=8310248&isnumber=8310156
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:85779
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Apr 2018 20:28
Last Modified:07 Aug 2018 19:55

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