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Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life

Smith, Jason A. D. and Armacost, Michelle and Ensign, Emily and Shaw, Susan and Jimenez, Nora and Millett, David and Liu, Charles and Heck, Christianne N. (2018) Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life. Epilepsy and Behavior, 83 . pp. 1-6. ISSN 1525-5050. doi:10.1016/j.yebeh.2018.03.015.

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Objective: The objective of this study was to investigate the effect of epilepsy surgery on depression, anxiety, and quality of life (QOL) in a Hispanic, primarily immigrant, Spanish-speaking population with intractable epilepsy (IE). Methods: Patients with IE from a comprehensive epilepsy treatment center in an urban, public healthcare setting who underwent resective brain surgery between 2008 and 2014 (N = 47) and completed presurgical and postsurgical neuropsychological evaluation were retrospectively identified. Presurgical and 1-year postsurgical Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), and QOLIE-31 ratings were analyzed as postsurgical outcome measures. One-tailed paired sample t-tests were used to evaluate whether scores improved postoperatively. Established severity level classifications of depression and anxiety (i.e., minimal, mild, moderate, or severe) were used to analyze changes in occurrence of depression and anxiety. Results: Medium to large improvements on the BDI-II and most QOLIE-31 subscales, with a smaller effect on the BAI and remaining QOLIE-31 subscales, were noted 1-year postsurgery. Levels of depression and anxiety were significantly reduced 1-year postsurgery. Depression, anxiety, and QOL improvements were robust and unaffected by gender, levels of education, or hemisphere of surgery. Conclusions: This study supports the positive benefits of epilepsy surgery on depression, anxiety, and QOL in Hispanic, primarily undocumented immigrant, Spanish-speaking people with epilepsy (PWE) in the US. These results are useful for educating this particular population about the possible benefits of surgery for IE and can enhance presurgical counseling.

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Additional Information:© 2018 Elsevier Inc. Received 8 December 2017, Revised 6 March 2018, Accepted 8 March 2018, Available online 7 April 2018. Statistical analysis conducted by Jason Smith, PhD, University of Texas Southwestern Medical Center. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Subject Keywords:Epilepsy surgery; Depression; Anxiety; Quality of life; Hispanics
Record Number:CaltechAUTHORS:20180416-082305242
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Official Citation:Jason A.D. Smith, Michelle Armacost, Emily Ensign, Susan Shaw, Nora Jimenez, David Millett, Charles Liu, Christianne N. Heck, Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life, Epilepsy & Behavior, Volume 83, June 2018, Pages 1-6, ISSN 1525-5050, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:85869
Deposited By: Tony Diaz
Deposited On:16 Apr 2018 21:24
Last Modified:15 Nov 2021 20:32

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