Komano, Tohru and Knippers, Rolf and Sinsheimer, Robert L. (1968) The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America, 59 (3). pp. 911-916. ISSN 0027-8424. PMCID PMC224778. https://resolver.caltech.edu/CaltechAUTHORS:KOMpnas68
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Abstract
In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during the subsequent period of single-strand DNA synthesis, while half remained in RF molecules. In this paper experiments are presented which permit a definition of the label remaining in the RF and which clarify the role of the RF in the synthesis of the progeny single-stranded DNA.
Item Type: | Article | ||||||||||||
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Additional Information: | © 1968 by the National Academy of Sciences. Communicated December 20, 1967. We are indebted to Dr. M. Goulian for a generous gift of purified exonuclease III and to Mrs. Louise Wilson for technical assistance. This research was supported in part by grant GM 13554 from the U.S. Public Health Service. | ||||||||||||
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Issue or Number: | 3 | ||||||||||||
PubMed Central ID: | PMC224778 | ||||||||||||
Record Number: | CaltechAUTHORS:KOMpnas68 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:KOMpnas68 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 8592 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Tony Diaz | ||||||||||||
Deposited On: | 21 Aug 2007 | ||||||||||||
Last Modified: | 02 Oct 2019 23:52 |
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