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Autoradiography of chromosomal DNA fibers from Chinese hamster cells

Huberman, Joel A. and Riggs, Arthur D. (1966) Autoradiography of chromosomal DNA fibers from Chinese hamster cells. Proceedings of the National Academy of Sciences of the United States of America, 55 (3). pp. 599-606. ISSN 0027-8424.

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Ignorance of the true length of the DNA molecules in the chromosomes of higher organisms has always been a major obstacle to understanding chromosome structure. Consequently, attempts have been made, usually with the aid of electron microscopy, to estimate the size of DNA in higher organisms. Solari (1) has reported the longest such DNA measured before now-a DNA fiber from a sea urchin sperm at least 93 μ, long.

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Additional Information:© 1966 by the National Academy of Sciences. Communicated by Norman Davidson, January 24, 1966. We gratefully acknowledge the advice and assistance of Dr. Giuseppe Attardi and of Dr. Herschel K. Mitchell, in whose laboratories this work was done. This work was supported by U.S. Public Health Service grants GM-11726 and 5-F1-GM-21,622 and by the Arthur McCallum Fund.
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Record Number:CaltechAUTHORS:HUBpnas66
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:8624
Deposited By: Tony Diaz
Deposited On:31 Aug 2007
Last Modified:02 Oct 2019 23:52

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