Cucullu, Michèle E. and Nolan, Steven P. and Belderrain, Tomàs R. and Grubbs, Robert H. (1999) Catalytic Dehalogenation of Aryl Chlorides Mediated by Ruthenium(II) Phosphine Complexes. Organometallics, 18 (7). pp. 1299-1304. ISSN 0276-7333. doi:10.1021/om980682n. https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626
Abstract
The catalytic dechlorination of aryl chlorides performed by RuHCl(H_2)_2(PCy_3)_2 and RuH_2(H_2)_2(PCy_3)_2 in alcohols is rapid and complete within 1 h. The mechanism involves a transfer hydrogenation step with participation of the alcohol. The system exhibits significant functional group tolerance. The catalyst can be generated in situ from [RuCl_2(COD)]_x (COD = cyclooctadiene) and 2 equiv of phosphine (PCy_3 or P^iPr_3). Catalytic conversions are similar to those observed when an isolated precatalyst is used. Mechanistic considerations and the scope of the process are discussed.
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Additional Information: | © 1999 American Chemical Society. Received August 11, 1998. The National Science Foundation is gratefully acknowledged for support of this work. | |||||||||
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Issue or Number: | 7 | |||||||||
DOI: | 10.1021/om980682n | |||||||||
Record Number: | CaltechAUTHORS:20180518-152454626 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626 | |||||||||
Official Citation: | Catalytic Dehalogenation of Aryl Chlorides Mediated by Ruthenium(II) Phosphine Complexes Michèle E. Cucullu, Steven P. Nolan, Tomás R. Belderrain, and Robert H. Grubbs Organometallics 1999 18 (7), 1299-1304 DOI: 10.1021/om980682n | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 86471 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | George Porter | |||||||||
Deposited On: | 21 May 2018 15:31 | |||||||||
Last Modified: | 15 Nov 2021 20:38 |
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