Cucullu, Michèle E. and Nolan, Steven P. and Belderrain, Tomàs R. and Grubbs, Robert H. (1999) Catalytic Dehalogenation of Aryl Chlorides Mediated by Ruthenium(II) Phosphine Complexes. Organometallics, 18 (7). pp. 1299-1304. ISSN 0276-7333. doi:10.1021/om980682n. https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626
![[img]](https://authors.library.caltech.edu/style/images/fileicons/application_pdf.png)
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626
Abstract
The catalytic dechlorination of aryl chlorides performed by RuHCl(H_2)_2(PCy_3)_2 and RuH_2(H_2)_2(PCy_3)_2 in alcohols is rapid and complete within 1 h. The mechanism involves a transfer hydrogenation step with participation of the alcohol. The system exhibits significant functional group tolerance. The catalyst can be generated in situ from [RuCl_2(COD)]_x (COD = cyclooctadiene) and 2 equiv of phosphine (PCy_3 or P^iPr_3). Catalytic conversions are similar to those observed when an isolated precatalyst is used. Mechanistic considerations and the scope of the process are discussed.
| Item Type: | Article | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Related URLs: |
| |||||||||
| ORCID: |
| |||||||||
| Additional Information: | © 1999 American Chemical Society. Received August 11, 1998. The National Science Foundation is gratefully acknowledged for support of this work. | |||||||||
| Funders: |
| |||||||||
| Issue or Number: | 7 | |||||||||
| DOI: | 10.1021/om980682n | |||||||||
| Record Number: | CaltechAUTHORS:20180518-152454626 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20180518-152454626 | |||||||||
| Official Citation: | Catalytic Dehalogenation of Aryl Chlorides Mediated by Ruthenium(II) Phosphine Complexes Michèle E. Cucullu, Steven P. Nolan, Tomás R. Belderrain, and Robert H. Grubbs Organometallics 1999 18 (7), 1299-1304 DOI: 10.1021/om980682n | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 86471 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | George Porter | |||||||||
| Deposited On: | 21 May 2018 15:31 | |||||||||
| Last Modified: | 15 Nov 2021 20:38 |
Repository Staff Only: item control page
