Distribution of endogenous murine leukemia virus DNA sequences among mouse chromosomes

Jolicoeur, Paul and Rassart, Eric and Kozak, Christine and Ruddle, Frank and Baltimore, David (1980) Distribution of endogenous murine leukemia virus DNA sequences among mouse chromosomes. Journal of Virology, 33 (3). pp. 1229-1235. ISSN 0022-538X. PMCID PMC288660. https://resolver.caltech.edu/CaltechAUTHORS:JOLjvir80

Preview

PDF - Published Version
See Usage Policy.
1MB

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:JOLjvir80

Abstract

We used mouse-Chinese hamster somatic cell hybrids which lose mouse chromosomes to examine the distribution of murine leukemia virus DNA sequences in the genome of A/HeJ mice. We analyzed total cellular DNA from various hybrid clones for the presence of viral sequences by molecular hybridization and used the Southern blot hybridization procedure to identify viral DNA in cellular restriction endonuclease fragments. Our results show that murine leukemia virus DNA sequences are distributed among many mouse chromosomes in this strain. Chromosome 4 was shown to contain murine leukemia virus DNA sequences.

Item Type:

Article

Related URLs:

URL	URL Type	Description
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC288660/	PubMed Central	Article
http://jvi.asm.org/cgi/content/abstract/33/3/1229	Other	UNSPECIFIED
http://jvi.asm.org/cgi/content/abstract/33/3/1229	Other	UNSPECIFIED

ORCID:

Author	ORCID
Baltimore, David	0000-0001-8723-8190

Additional Information:

© 1980 American Society for Microbiology. We thank Peter Shank for his advice on the DNA transfer technique. This project was supported by grants from the National Cancer Institute of Canada and the Medical Research Council to P.J., by Public Health Service grant 09966 to F.R., and by grant VC-4G from the American Cancer Society and Public Health Service grant CA-14051 from the National Cancer Institute to DB.

Funders:

Funding Agency	Grant Number
National Cancer Institute of Canada	UNSPECIFIED
Medical Research Council of Canada	UNSPECIFIED
NIH	09966
American Cancer Society	VC-4G
NIH	CA-14051

Issue or Number:

PubMed Central ID:

PMC288660

Record Number:

CaltechAUTHORS:JOLjvir80

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:JOLjvir80

Usage Policy:

No commercial reproduction, distribution, display or performance rights in this work are provided.

ID Code:

8722

Collection:

CaltechAUTHORS

Deposited By:

Archive Administrator

Deposited On:

10 Sep 2007

Last Modified:

02 Oct 2019 23:53

Repository Staff Only: item control page