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Flexible-Device Injector with a Microflap Array for Subcutaneously Implanting Flexible Medical Electronics

Song, Kwangsun and Kim, Juho and Cho, Sungbum and Kim, Namyun and Jung, Dongwuk and Choo, Hyuck and Lee, Jongho (2018) Flexible-Device Injector with a Microflap Array for Subcutaneously Implanting Flexible Medical Electronics. Advanced Healthcare Materials, 7 (15). Art. No. 1800419. ISSN 2192-2640. http://resolver.caltech.edu/CaltechAUTHORS:20180626-151042069

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Abstract

Implantable electronics in soft and flexible forms can reduce undesired outcomes such as irritations and chronic damages to surrounding biological tissues due to the improved mechanical compatibility with soft tissues. However, the same mechanical flexibility also makes it difficult to insert such implants through the skin because of reduced stiffness. In this paper, a flexible‐device injector that enables the subcutaneous implantation of flexible medical electronics is reported. The injector consists of a customized blade at the tip and a microflap array which holds the flexible implant while the injector penetrates through soft tissues. The microflap array eliminates the need of additional materials such as adhesives that require an extended period to release a flexible medical electronic implant from an injector inside the skin. The mechanical properties of the injection system during the insertion process are experimentally characterized, and the injection of a flexible optical pulse sensor and electrocardiogram sensor is successfully demonstrated in vivo in live pig animal models to establish the practical feasibility of the concept.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1002/adhm.201800419DOIArticle
ORCID:
AuthorORCID
Choo, Hyuck0000-0002-8903-7939
Additional Information:© 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim. Manuscript received: 19 April 2018. Manuscript revised: 30 May 2018. Version of Record online: 25 June 2018. Issue Online: 08 August 2018. Funding Information: National Research Foundation of Korea. Grant Number: 2016R1A2B4012854. GIST‐Caltech Research Collaboration.
Funders:
Funding AgencyGrant Number
National Research Foundation of Korea2016R1A2B4012854
GIST-Caltech Research CollaborationUNSPECIFIED
Subject Keywords:biosensors; flexible implants; implantable devices; medical electronics; medical implant injectors
Record Number:CaltechAUTHORS:20180626-151042069
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20180626-151042069
Official Citation:K. Song, J. Kim, S. Cho, N. Kim, D. Jung, H. Choo, J. Lee, Adv. Healthcare Mater. 2018, 7, 1800419. https://doi.org/10.1002/adhm.201800419
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:87358
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:26 Jun 2018 22:19
Last Modified:13 Aug 2018 23:30

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