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Specific protection from phenocopy induction by heat shock

Mitchell, Herschel K. and Moller, Galina and Petersen, Nancy S. and Lipps-Sarmiento, Loveriza (1979) Specific protection from phenocopy induction by heat shock. Genesis, 1 (2). pp. 181-192. ISSN 1526-954X. doi:10.1002/dvg.1020010206.

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Mild heat treatments applied to whole animals or cell cultures of Drosophila prior to lethal heat shocks result in increased survival and protection against phenocopy induction. The optimal condition for the preliminary mild heat treatment is that which induces the synthesis of heat‐shock proteins but does not turn off the protein synthesis that is in progress. Recovery of protein synthesis but not RNA synthesis following a drastic heat shock is much enhanced by the pretreatments. The results suggest that the protection for survival and against phenocopy induction is due to storage of messenger RNA.

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Additional Information:© 1979 Wiley‐Liss, Inc. Manuscript accepted: 14 September 1979; Manuscript received: 16 July 1979.
Subject Keywords:drosophila; gene regulation; heat shock; protection phenocopies; survival
Issue or Number:2
Record Number:CaltechAUTHORS:20180629-105630545
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Official Citation:Mitchell, H. K., Moller, G. , Petersen, N. S. and Lipps‐Sarmiento, L. (1979), Specific protection from phenocopy induction by heat shock. Dev. Genet., 1: 181-192. doi:10.1002/dvg.1020010206
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:87471
Deposited By: Tony Diaz
Deposited On:29 Jun 2018 18:20
Last Modified:15 Nov 2021 20:48

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